Results 41 to 50 of about 4,436,011 (309)

Rho Family GTPases and Rho GEFs in Glucose Homeostasis

Cells, 2021
Dysregulation of glucose homeostasis leading to metabolic syndrome and type 2 diabetes is the cause of an increasing world health crisis. New intriguing roles have emerged for Rho family GTPases and their Rho guanine nucleotide exchange factor (GEF ...
Polly A. Machin, Elpida Tsonou, David C. Hornigold, Heidi C. E. Welch   +3 more
doaj   +1 more source

Development and validation of new evaluation scale for measuring stroke patients' motivation for rehabilitation in rehabilitation wards.

PLoS ONE, 2022
ObjectiveThis study aimed to develop the Motivation in stroke patients for rehabilitation scale (MORE scale), following the Consensus-based standards for the selection of health measurement instruments (COSMIN).MethodStudy participants included ...
Taiki Yoshida, Yohei Otaka, Shin Kitamura, Kazuki Ushizawa, Masashi Kumagai, Yuto Kurihara, Jun Yaeda, Rieko Osu   +7 more
doaj   +2 more sources

Transcription termination factor Rho is essential for Micrococcus luteus [PDF]

Journal of Bacteriology, 1997
The growth of Micrococcus luteus, a soil microorganism that belongs to the high-G+C gram-positive phylogenetic group, is prevented by bicyclomycin, an antibiotic that inhibits the activity of the M. luteus transcription termination factor Rho. A mutant that can grow in 0.3 mM bicyclomycin has a Rho that is insensitive to bicyclomycin and has the single
W L, Nowatzke, E, Keller, G, Koch, J P, Richardson   +3 more
openaire   +2 more sources

A dispersive analysis of the pion vector form factor and $$\tau ^{-}\rightarrow K^{-}K_{S}\nu _{\tau }$$ τ-→K-KSντ decay

European Physical Journal C: Particles and Fields, 2019
We explore the potential of a combined analysis of the decays $$\tau ^{-}\rightarrow \pi ^{-}\pi ^{0}\nu _{\tau }$$ τ-→π-π0ντ and $$\tau ^{-}\rightarrow K^{-}K_{S}\nu _{\tau }$$ τ-→K-KSντ in the determination of the $$\rho (1450)$$ ρ(1450) and $$\rho ...
Sergi Gonzàlez-Solís, Pablo Roig
doaj   +1 more source

The Rho-Dependent Transcription Termination Is Involved in Broad-Spectrum Antibiotic Susceptibility in Escherichia coli

Frontiers in Microbiology, 2020
One of the major ways of acquiring multidrug resistance in bacteria is via drug influx and efflux pathways. Here, we show that E. coli with compromised Rho-dependent transcription termination function has enhanced broad-spectrum antibiotic susceptibility,
Md. Hafeezunnisa, Md. Hafeezunnisa, Ranjan Sen   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Mechanical stress regulates gene expression via Rho/Rho-kinase signaling pathway

Journal of Physical Fitness and Sports Medicine, 2015
Exercise improves the performance of the cardiovascular system, striated muscle, and bones, and reduces obesity. Exercise provides for mechanical forces, which include fluid flow and stretching.
Takako Kaneko-Kawano, Kenji Suzuki
doaj   +1 more source

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901), Barbara D. Smith (2212672), Takahashi, A, Christopher Denton, Layne, MD, Bahja Ahmed-Abdi, Ayuko Takahashi, Suki, B, Nikitorowicz-Buniak, J, Bela Suki (2212681), Bahja Ahmed-Abdi (2212675), Matthew D. Layne (364786), Markella Ponticos, Ahmed-Abdi, B, Robert Lafyatis, Markella Ponticos (2212669), Xu Shiwen (2212678), Stratton, R, Bela Suki, Barbara D Smith, Richard Stratton (776213), Joanna Nikitorowicz-Buniak (776212), Smith, BD, Christopher Denton (276245), Xu Shiwen, Lafyatis, R, David Abraham (36404), Shiwen, X, David Abraham, Abraham, D, Matthew D Layne, Ponticos, M, Denton, C, Joanna Nikitorowicz-Buniak, Robert Lafyatis (38139), Richard Stratton   +35 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Hyperbolic form factors for Yukawa interactions, and applications to the Earth

European Physical Journal C: Particles and Fields
We define the hyperbolic form factor of a density distribution as its bilateral Laplace transform, related by duality or analytic continuation to its ordinary form factor.  For a sphere it is given by $$\Phi (x \!= \! kR) =\langle \,\cosh \,\vec k.\vec r\
Pierre Fayet
doaj   +1 more source