Results 91 to 100 of about 42,798 (278)
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba +4 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang +16 more
wiley +1 more source
Spatiotemporal Control of Intracellular Membrane Trafficking by Rho GTPases
Cells, 2019 As membrane-associated master regulators of cytoskeletal remodeling, Rho GTPases coordinate a wide range of biological processes such as cell adhesion, motility, and polarity.
Monilola A. Olayioye +2 more
doaj +1 more source
Avaliação, in vivo e in vitro, da reatividade vascular renal à vasopressina em ratos endotoxêmicos: importância da via Rho-A/Rho-quinase [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaSepse é uma infecção local, acompanhada de uma resposta inflamatória sistêmica e vinculada à elevada incidência e ...
Guarido, Karla Lorena
core
Rho GTPases in cancer cell biology
, 2008 Rho GTPases contribute to multiple cellular processes that could affect cancer progression, including cytoskeletal dynamics, cell cycle progression, transcriptional regulation, cell survival and vesicle trafficking.
Vega, F M +5 more
core +1 more source
Cytometry Part A, EarlyView.ABSTRACT Cell‐in‐cell (CIC) structures are among the most intriguing cellular phenomena occasionally observed in human cancer specimens. Once regarded as incidental findings, accumulating evidence has linked specific CIC subtypes, particularly entosis, to tumor progression and patient prognosis.
Maria V. Leyba‐Mesa +4 more
wiley +1 more source
Rho GTPases in the Physiology and Pathophysiology of Peripheral Sensory Neurons
Cells, 2019 Numerous experimental studies demonstrate that the Ras homolog family of guanosine triphosphate hydrolases (Rho GTPases) Ras homolog family member A (RhoA), Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division cycle 42 (Cdc42) are ...
Theodora Kalpachidou +3 more
doaj +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
The Role of Rho GTPases in Motility and Invasion of Glioblastoma Cells
Analytical Cellular Pathology, 2020 Astrocytomas are primary malignant brain tumors that originate from astrocytes. Grade IV astrocytoma or glioblastoma is a highly invasive tumor that occur within the brain parenchyma. The Rho family of small GTPases, which includes Rac1, Cdc42, and RhoA,
Houssam Al-Koussa +4 more
doaj +1 more source