Results 111 to 120 of about 37,687 (240)

Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Sampayo RG   +4 more
europepmc   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

open access: yesMolecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol   +5 more
wiley   +1 more source

TipQuant: a robust algorithm for quantitative analysis of spatiotemporally dynamic activities in tip‐growing cells

open access: yesNew Phytologist, EarlyView.
Tip Quantification enables quantitative analyses over versatile selections of regions of interest. Summary Cell polarity and tip growth rely on the dynamic spatial organization of signaling and structural components. Quantitative characterization of these spatiotemporal dynamics is critical for understanding polarized cell growth, yet manual ...
Jingzhe Guo   +7 more
wiley   +1 more source

Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases. [PDF]

open access: yesNat Commun, 2023
Cheng X   +13 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani   +5 more
wiley   +1 more source

DOCK4 Regulation of Rho GTPases Mediates Pulmonary Vascular Barrier Function. [PDF]

open access: yesArterioscler Thromb Vasc Biol, 2022
Yazbeck P   +12 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Role of Rho GTPases in stem cell regulation. [PDF]

open access: yesBiochem Soc Trans, 2021
Zhang Z, Liu M, Zheng Y.
europepmc   +1 more source

Home - About - Disclaimer - Privacy