Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
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Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities. [PDF]
Biochem Soc TransBeaudin A, Lefrançois P, Laurin M.
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Rho GTPases in Retinal Vascular Diseases. [PDF]
Int J Mol Sci, 2021 Uemura A, Fukushima Y.
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Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response
Glia, Volume 74, Issue 9, September 2026.Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala +6 more
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Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li +3 more
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Profiling Ten RHO GTPases in Myeloid Malignancies Reveals Distinct Expression Patterns and Prognostic Associations. [PDF]
Cancer Medde Almeida Rodrigues B +5 more
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Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
MedComm, Volume 7, Issue 9, September 2026.Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
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An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]
J Biol ChemMarcus K +3 more
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Genetic analyses of leaf traits in an interspecific Zoysia japonica × Zoysia matrella F2 population
The Plant Genome, Volume 19, Issue 3, September 2026.Abstract Zoysiagrass (Zoysia spp.) is an important warm‐season turfgrass cultivated across tropical, subtropical, and temperate regions of the world. The genus is characterized by the presence of salt‐secreting glands on the adaxial leaf surface, which contribute to its high salt tolerance.
Shreena Pradhan +5 more
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Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
Andrology, Volume 14, Issue 6, Page 1831-1846, September 2026.ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
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