Results 141 to 150 of about 37,687 (240)

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro. [PDF]

PLoS One, 2023
Koch D, Kho AL, Fukuzawa A, Alexandrovich A, Vanaanen KJ, Beavil A, Pfuhl M, Rees M, Gautel M.   +8 more
europepmc   +1 more source

Oxidative stress and Rho GTPases in the biogenesis of tunnelling nanotubes: implications in disease and therapy. [PDF]

Cell Mol Life Sci, 2021
Raghavan A, Rao P, Neuzil J, Pountney DL, Nath S.   +4 more
europepmc   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, Volume 143, Issue 5, Page 625-638, September 2026.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Somatic mutations in IRE1α regulate keratinocyte migration and survival by differentially activating Rho GTPases. [PDF]

J Cell Sci
Mogre S, Robinson L, Sethia K, Rimal B, Son J, Pacifico C, Santy L, Patterson A, Glick AB.   +8 more
europepmc   +1 more source

Staurosporine Drives Non‐Canonical Melanocyte Maturation by Coupling β‐Catenin Signaling to Actin‐Dependent Dendrite Remodeling

Pigment Cell &Melanoma Research, Volume 39, Issue 5, September 2026.
Staurosporine drives non‐canonical melanocyte maturation through β‐catenin‐dependent actin remodeling. Functional maturation enhances dendrite architecture and melanogenic differentiation without inducing melanocyte proliferation, providing a biological framework for restoring functional melanocytes in acquired hypopigmentary disorders.
Kangning Xu, Lingli Yang, Sylvia Lai, Fei Yang, Yasutaka Kuroda, Daisuke Tsuruta, Ichiro Katayama   +6 more
wiley   +1 more source

Redox response feature and mechanism of Arf1 and their implications for those of Ras and Rho GTPases. [PDF]

J Biol Chem
Johnson HE, Banks EL, Ozuna OS, Heo J.
europepmc   +1 more source

Seeing is believing: tools to study the role of Rho GTPases during cytokinesis. [PDF]

Small GTPases, 2022
Koh SP, Pham NP, Piekny A.
europepmc   +1 more source

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases. [PDF]

Toxicol Sci
Zelko IN, Hussain A, Malovichko MV, Wickramasinghe NS, Srivastava S.   +4 more
europepmc   +1 more source

Modification of the Transcription Factor FOXL2 at Serines 101 and 107 Disables DNA Binding, Leads to Nucleolar Relocalization, and Rewires Granulosa‐Cell Programs

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
PKC‐mediated phosphorylation of FOXL2 weakens DNA binding, alters subnuclear localization and protein interactions, and reshapes FOXL2‐dependent transcriptional programs in granulosa cells, supporting a reversible mechanism that modulates FOXL2 activity through phosphorylation of its DNA‐binding domain. ABSTRACT FOXL2 is a forkhead transcription factor
Ludovic Mousseron, Despoina Chousianiti, Francis Poulat, Bérangère Legois, Reiner A. Veitia, Anne‐Laure Todeschini   +5 more
wiley   +1 more source