Results 141 to 150 of about 104,378 (298)

High-throughput sequencing identified circular RNA circUBE2K mediating RhoA associated bladder cancer phenotype via regulation of miR-516b-5p/ARHGAP5 axis [PDF]

, 2021
Chen Yang, Zezhong Mou, Siqi Wu, Yuxi Ou, Zheyu Zhang, Xinan Chen, Xiyu Dai, Chenyang Xu, Shanhua Mao, Haowen Jiang   +9 more
openalex   +1 more source

Identification of actionable targets using DEPArray‐based sorting of pure carcinoma and stromal populations from formalin‐fixed paraffin‐embedded tissues followed by shallow whole‐genome sequencing

The Journal of Pathology, EarlyView.
Abstract Formalin‐fixed paraffin‐embedded (FFPE) tissue specimens represent precious resources for clinical genomic profiling studies, especially when coupled with comprehensive medical records. Even though next‐generation sequencing (NGS) is an effective tool to detect somatic mutations and somatic copy number alterations (sCNA), the biggest ...
Georgios Nteliopoulos, Evie Wren, Amelia Rushton, Marc K Wadsley, Daniel Fernandez‐Garcia, Floriana Manodoro, Otis Agbaimoni, Ritika Chauhan, Zhao Cheng, Darren P Ennis, Karen Page, Rebecca C Allsopp, Joel Bautista, Ignazio Puccio, Nik Matthews, Kelly LT Gleason, Rehman Farah, Laura Kenny, Iain A McNeish, Jacqueline A Shaw, R Charles Coombes   +20 more
wiley   +1 more source

RhoA- and Ran-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

, 2020
Benoît Dehapiot, R Clément, A Bourdais, Sébastien Huet, Guillaume Halet   +4 more
openalex   +1 more source

Structure–Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents [PDF]

, 2023
Akhila Dandamudi, William Seibel, Benjamin E. Tourdot, José A. Cancelas, Huzoor Akbar, Yi Zheng   +5 more
openalex   +1 more source

Microservices and Machine Learning Algorithms for Adaptive Green Buildings [PDF]

, 2019
In recent years, the use of services for Open Systems development has consolidated and strengthened. Advances in the Service Science and Engineering (SSE) community, promoted by the reinforcement of Web Services and Semantic Web technologies and the ...
Alonso Montesinos, Joaquín Blas, Ayala Palenzuela, Rosa María, Capobianco Uriarte, María De Las Mercedes, Criado Rodríguez, Javier, Iribarne Martínez, Luis Fernando, Piedra Fernández, José Antonio, Rodríguez Gracia, Diego   +6 more
core   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization

, 2009
Deepak Kumar, Andrew B. Lassar
openalex   +1 more source

DIFFERENTIAL RHOA ACTIVITY IN CHONDROCYTES UNDER FLOW [PDF]

, 2012
poster abstractMechanical force environment is a major factor that influences cellular homeostasis and remodeling. The prevailing wisdom in this field demon-strated that a threshold of mechanical forces or deformation was required to affect cell ...
Na, Sungsoo, Wan, Qiaoqiao, Yokota, Hiroki   +2 more
core  

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

PROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq, Alin Rai, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, David W. Greening, Richard J. Simpson   +6 more
wiley   +1 more source

Single-component optogenetic tools for inducible RhoA GTPase signaling [PDF]

, 2021
Erin E. Berlew, Ivan A. Kuznetsov, Keisuke Yamada, Lukasz J. Bugaj, Joel D. Boerckel, Brian Y. Chow   +5 more
openalex   +1 more source