Results 81 to 90 of about 99,117 (203)
RhoA activation in axotomy-induced neuronal death [PDF]
Experimental Neurology, 2018 After spinal cord injury (SCI) in mammals, severed axons fail to regenerate, due to both extrinsic inhibitory factors, e.g., the chondroitin sulfate proteoglycans (CSPGs) and myelin-associated growth inhibitors (MAIs), and a developmental loss of intrinsic growth capacity. The latter is suggested by findings in lamprey that the 18 pairs of individually
Guixin Zhang +4 more
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RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance
Stem Cell Reports, 2017 Summary: RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation.
Ming Liu +12 more
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RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin
Cells, 2020 RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated ...
Dandan Tan +9 more
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RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation. [PDF]
PLoS ONE, 2013 RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation.
Aae Suzuki +11 more
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Yersinia type III secretion : send in the effectors [PDF]
, 2002 Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block ...
Cornelis, G. R.
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Cancer Management and Research, 2020 Pengfei Li,1,* Huina Lv,2,* Min Xu,1 Bin Zang,1 Yegang Ma1 1Department of Thoracic Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, People’s Republic of China; 2Department of Ultrasound,
Li P, Lv H, Xu M, Zang B, Ma Y
doaj
RhoA controls furrow formation
The Journal of Cell Biology, 2005 Evidence that the cytokinetic apparatus is dependent on spindle microtubules comes primarily from classical experiments in which the spindle was manually moved or disrupted. On page 91, Bement et al. reveal the physiology that underlies these findings.
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Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
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Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
, 2016 open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
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A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts
Cell Reports, 2017 The small GTPase RhoA is involved in a variety of fundamental processes in normal tissue. Spatiotemporal control of RhoA is thought to govern mechanosensing, growth, and motility of cells, while its deregulation is associated with disease development ...
Max Nobis +42 more
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