Characterization of rhodanese synthesized by the wild and EMS-mutated Klebsiella oxytoca JCM1665
Journal of Agriculture and Food ResearchCyanide poisoning remains a significant concern for both civilian and military personnel worldwide. Rhodanese, a cyanide detoxify enzyme produced by the wild (KOJCM1665) and two selected mutant strains (KOJCM1665c and KOJCM1665d) of Klebsiella oxytoca ...
Babamotemi Oluwasola Itakorode +3 more
doaj +1 more source
Environmental risk assessments of uses cyanide in gold extraction on water quality parameters and its effect on rhodanese activities in selected organs of coptodon zillii in igun reservoir, Southwestern, Nigeria [PDF]
, 2022 Oluwakemi Victoria Okunola +5 more
openalex +1 more source
The refolding of recombinant human liver methylmalonyl-CoA mutase from inclusion bodies produced in Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1998 Human methylmalonyl-CoA mutase (hMCM) is an adenosylcobalamin-dependent enzyme that catalyses the structural rearrangement of (R)-methylmalonyl-CoA to succinyl-CoA as pan of the catabolism of the branched chain amino acids valine, leucine and isoleucine,
Hayes, Michelle Marie
core
Molecular Microbiology, Volume 124, Issue 3, Page 204-220, September 2025.In Hyphomicrobium denitrificans, the use of thiosulfate as a supplemental electron donor is regulated by two homologous sulfane‐sulfur responsive ArsR‐type transcriptional repressors, sHdrR and SoxR, that act cooperatively. Remarkably, the regulation by sHdrR/SoxR extends far beyond sulfur oxidation and deeply affects anaerobic metabolism, particularly
Jingjing Li +3 more
wiley +1 more source
Allyl sulfur compounds and cellular detoxification system: effects and perspectives in cancer therapy [PDF]
, 2011 Natural organosulfur compounds (OSCs) have been shown to have chemopreventive effects and to suppress the proliferation of tumor cells in vitro through the induction of apoptosis.
Melino, S, Paci, M, Sabelli, R
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Continuous chemotrophic growth and respiration of Chromatiaceae species at low oxygen concentrations [PDF]
, 1992 Endogenous and maximum respiration rates of nine purple sulfur bacterial strains were determined. Endogenous rates were below 10 nmol O2 · (mg protein · min)-1 for sulfur-free cells and 15–35 nmol O2 · (mg protein · min)-1 for cells containg ...
Overmann, Jörg, Pfennig, Norbert
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Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
The FASEB Journal, Volume 39, Issue 12, 30 June 2025.Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source
mSphere, 2018 Gut microbes can enhance the ability of hosts to consume secondary plant compounds and, therefore, expand the dietary niche breadth of mammalian herbivores.
Lifeng Zhu +7 more
doaj +1 more source
Frontiers in Microbiology, 2020 Here, we experimentally expand understanding of the reactions and enzymes involved in Acidithiobacillus thiooxidans ATCC 19377 S0 and S2O32- metabolism by developing models that integrate gene expression analyzed by RNA-Seq, solution sulfur speciation ...
David Camacho +10 more
doaj +1 more source
Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production [PDF]
, 2005 Heat shock protein 10 (Hsp10) and heat shock protein 160 (Hsp60) were originally described as essential mitochondrial proteins involved in protein folding.
Banovic, T +9 more
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