Results 1 to 10 of about 8,823 (166)

Historical studies on the use of Rhubarb in Japan [PDF]

Frontiers in Pharmacology
BackgroundRhubarb product is the crude drug derived from the root or rhizome of Rheum or other related plants, and has been used since ancient times in Asian and European countries.
Misato Ota, Toshiaki Makino
doaj   +2 more sources

Rhubarb as a Potential Component of an Anti-Inflammatory Diet [PDF]

Foods
As a critical element of many civilization diseases, inflammation is a challenge for research on the development of effective treatment or preventive therapies.
Joanna Kolodziejczyk-Czepas, Jan Czepas
doaj   +2 more sources

Inulin increases the beneficial effects of rhubarb supplementation on high-fat high-sugar diet-induced metabolic disorders in mice: impact on energy expenditure, brown adipose tissue activity, and microbiota

Gut Microbes, 2023
Consumption of prebiotics and plant-based compounds have many beneficial health effects through modulation of gut microbiota composition and are considered as promising nutritional strategy for the treatment of metabolic diseases.
Marion Regnier, , Patrice D. Cani
exaly   +3 more sources

Rhubarb: Traditional Uses, Phytochemistry, Multiomics-Based Novel Pharmacological and Toxicological Mechanisms [PDF]

Drug Design, Development and Therapy
Hua Miao,1 Kai-En Wang,1 Ping Li,2 Ying-Yong Zhao1 1School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Beijing Key Laboratory for Immune-Mediated Inflammatory Diseases, China-Japan Friendship ...
Miao H, Wang KE, Li P, Zhao YY
doaj   +2 more sources

Rhubarb enhances gastrointestinal motility via calcium-mediated intestinal acetylcholine release: a network pharmacology study [PDF]

Scientific Reports
Rapid restoration of intestinal motility is crucial in managing acute pancreatitis (AP), particularly in severe cases. This study aims to investigate the potential of Chinese medicinal rhubarb to enhance bowel motility through modulation of calcium ion ...
Zhiyong Wen, Weihua Liu, Jialing Li, Songling Tan, Jianbo Wen   +4 more
doaj   +2 more sources

Research Progress on the Anti-Liver Cancer Mechanism and Toxicity of Rhubarb Anthraquinone [PDF]

Drug Design, Development and Therapy
Linyuan Yu,1,2 Jinxing Qin,2 Mei Zhang,3 Yawen Gao,4 Yongli Zhao1 1Department of Pharmacy, Chengdu Integrative TCM & Western Medicine Hospital, Chengdu, Sichuan, 610095, People’s Republic of China; 2Department of Pharmacy, Sichuan Second Hospital of T.C ...
Yu L, Qin J, Zhang M, Gao Y, Zhao Y
doaj   +2 more sources

Realgar-Induced CNS Toxicity: Exploring OTC-Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver-Brain Axis. [PDF]

Adv Sci (Weinh)
Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ye P, Li Z, Fu H, Wang S, Cui X, Song C, Ma C, Jiang H.   +7 more
europepmc   +2 more sources

The impact of rhubarb (Rheum Ribes L.) juice-based marinade on the quality characteristics and microbial safety of chicken breast fillets during refrigerated storage [PDF]

Poultry Science
Acidic marinades are commonly used to improve the quality meat products. However, no study has been performed to determine the effects of rhubarb juice as a marinating liquid on the quality parameters of chicken breast fillets.
Pınar Karatepe, Gökhan Kürşad İncili, Ali Tekin, Mehmet Çalıcıoğlu, Müzeyyen Akgöl, Ali Adnan Hayaloğlu   +5 more
doaj   +2 more sources

Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm [PDF]

Heliyon
Aim of the study: The aim of this study was to systematically investigate the effects and mechanisms of Rhubarb in the treatment of Atherosclerosis (AS) and Abdominal Aortic Aneurysm (AAA) by utilizing network pharmacology and molecular docking ...
Huilin Xu, Jun Huang, Youjie Zeng, Xia Wang, Huilin Lian, Siyi Zhang, Ren Guo   +6 more
doaj   +2 more sources

Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer [PDF]

Drug Design, Development and Therapy
Anni Zhao,1,* Xiaomei Liu,1,* Xiping Chen,1,* Sha Na,1,* Hui Wang,1 Xuan Peng,1 Peizhong Kong,1 Lu Li1,2 1Department of Biochemistry and Molecular Biology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese ...
Zhao A, Liu X, Chen X, Na S, Wang H, Peng X, Kong P, Li L   +7 more
doaj   +2 more sources