Results 31 to 40 of about 8,823 (166)

Identification of the multiple bioactive derivatives and their endogenous molecular targets that may mediate the laxative effect of rhubarb in rats

open access: yesJournal of Traditional Chinese Medical Sciences, 2020
Objective: To determine the mechanism of the laxative effect of rhubarb (Rheum tanguticum Maxim. ex Balf.) in rats using a combined bioinformatic and in vivo approach.
Lei Xie   +8 more
doaj   +1 more source

Qualitative and quantitative analysis methods for quality control of rhubarb in Taiwan’s markets

open access: yesFrontiers in Pharmacology
Introduction: Rhubarb is a traditional Chinese medicine (TCM) used to release heat and has cathartic effects. Official rhubarb in Taiwan Herbal Pharmacopeias 4th edition (THP 4th) and China Pharmacopeia 2020 (CP 2020) are the roots and rhizomes of Rheum ...
Thanh-Thuy-Dung Au   +2 more
doaj   +1 more source

The application of rhubarb concoctions in traditional Chinese medicine and its compounds, processing methods, pharmacology, toxicology and clinical research

open access: yesFrontiers in Pharmacology
ObjectiveThis study reviews the development of rhubarb processing and the current status of pharmacological research. We summarized the effects of different processing methods on the active compounds, pharmacological effects, and toxicity of rhubarb, as ...
Yi Wen   +6 more
doaj   +1 more source

Integrated assessment of medicinal rhubarb by combination of delayed luminescence and HPLC fingerprint with emphasized on bioactivities based quality control

open access: yesChinese Medicine, 2020
Background To promote herbal medicine depends largely on its quality. Chromatographic fingerprint is a frequent approach for quality assessment of herbs however with challenges on robust and reproducibility.
Mengmeng Sun   +13 more
doaj   +1 more source

Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology

open access: yesDrug Design, Development and Therapy, 2021
Shanze Li,* Yuming Wang,* Chunyan Li, Na Yang, Hongxin Yu, Wenjie Zhou, Siyu Chen, Shenshen Yang, Yubo Li Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China*These authors contributed equally to this ...
Li S   +8 more
doaj  

Application of multifunctional compositions based on Rheum rhaponticum L. extracts for the elaboration of plant protection products

open access: yesОвощи России, 2020
Relevance.Extract-based compositions, combining various types of biological activity were created and tested, to reveal the potential of genus Rheum (Polygonaceae)plants bioactive substances.
A. A. Gladcaia
doaj   +1 more source

Mechanism of rhubarb in the treatment of hyperlipidemia: A recent review

open access: yesOpen Medicine, 2023
Hyperlipidemia is a metabolic disorder, which is a major risk factor for atherosclerosis, stroke, and coronary heart disease. Although lipid-lowering treatments have been extensively studied, safer treatments with fewer adverse effects are needed ...
Wu Lijiao   +5 more
doaj   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Turnip mosaic virus in rhubarb grown on farms in Poland [PDF]

open access: yesJournal of Plant Protection Research
The aim of this study was the detection and molecular characterization of newly identified turnip mosaic virus (TuMV) isolates infecting rhubarb in Poland. The presence of the virus in rhubarb was confirmed by ELISA and RT-PCR techniques. The specificity
Beata Komorowska   +2 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

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