Results 51 to 60 of about 8,823 (166)

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian   +8 more
wiley   +1 more source

Three Men and an Abbey: The Cornaro Triple Portrait☆

open access: yesRenaissance Studies, Volume 40, Issue 1, Page 97-120, February 2026.
Abstract This paper builds on the author’s recent identification of an early sixteenth‐century painting in the National Gallery of Ireland as containing rare portraits of Giorgio Cornaro (brother of Caterina, Queen of Cyprus) and his son Cardinal Francesco.
Rachel Healy
wiley   +1 more source

DNA barcoding combined with high-resolution melting analysis to discriminate rhubarb species and its traditional Chinese patent medicines

open access: yesFrontiers in Pharmacology
Introduction: Rhubarb is a frequently used and beneficial traditional Chinese medicine. Wild resources of these plants are constantly being depleted, meaning that rhubarb products have been subjected to an unparalleled level of adulteration ...
Luyi Shen   +12 more
doaj   +1 more source

Untargeted metabolomics reveals dose-response characteristics for effect of rhubarb in a rat model of cholestasis

open access: yesFrontiers in Pharmacology, 2016
Cholestasis is a serious manifestation of liver diseases with limited therapies. Rhubarb, a widely used herbal medicine, has been frequently used at a relatively large dose for treating cholestasis.
Cong-En eZhang   +23 more
doaj   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

open access: yesAggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang   +12 more
wiley   +1 more source

Matrix Metalloproteinase Inhibition in Melanoma

open access: yesExperimental Dermatology, Volume 35, Issue 1, January 2026.
ABSTRACT Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix (ECM) and are found to participate in all stages of tumour progression including modifying signalling pathways, regulating cytokines and promoting tumour growth, particularly by inducing angiogenesis and facilitating cancer spread.
Ellie Zhang   +2 more
wiley   +1 more source

Zengwei Chengqi Decoction Reduces Inflammation in Acute Intestinal Obstruction

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Objective This study investigates the therapeutic effects of Zengwei Chengqi Decoction (ZW) on acute intestinal obstruction (AIO), focusing on its ability to alleviate inflammation and reduce associated tissue damage. Network pharmacology and experimental animal models were used to explore the mechanisms of action.
Ying Gong   +9 more
wiley   +1 more source

Commodity risk assessment of Vitis spp. plants from Moldova

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission requests EFSA to provide scientific opinions in the field of plant health in accordance with Article 29 of Regulation (EC) No 178/2002. Annex VI of Commission Implementing Regulation (EU) 2019/2072 lists plants, plant products and other objects whose introduction into the Union from certain third countries is prohibited.
EFSA Panel on Plant Health (PLH)   +37 more
wiley   +1 more source

Modification of the existing maximum residue levels for deltamethrin in kiwi, melons and watermelons

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Bayer AG Crop Science Division submitted a request to the competent national authority in Austria to modify the existing maximum residue levels (MRLs) for the active substance deltamethrin in kiwi, melons and watermelons.
EFSA (European Food Safety Authority)   +18 more
wiley   +1 more source

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