Results 101 to 110 of about 78,533 (349)

Riboflavin Inhibits IL-6 Expression and p38 Activation in Islet Cells

Cell Transplantation, 2008
Riboflavin is a water-soluble vitamin that reduces the production of proinflammatory mediators and oxygen radicals. Because islet β-cells are very sensitive to oxidative stress and to cytokines, we investigated the possible cytoprotective effects of ...
Lorenzo Cobianchi, Alessia Fornoni, Antonello Pileggi, R. Damaris Molano, Nahir Y. Sanabria, Jorge Gonzalez-Quintana, Nicola Bocca, Simona Marzorati, Elsie Zahr, Anthony R. Hogan, Camillo Ricordi, Luca Inverardi M.D.   +11 more
doaj   +1 more source

Statistical significance in high-dimensional linear mixed models [PDF]

arXiv, 2019
This paper concerns the development of an inferential framework for high-dimensional linear mixed effect models. These are suitable models, for instance, when we have $n$ repeated measurements for $M$ subjects. We consider a scenario where the number of fixed effects $p$ is large (and may be larger than $M$), but the number of random effects $q$ is ...
arxiv  

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

ChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout, Marie‐Christine Maurel   +1 more
wiley   +1 more source

Fluorescence Spectroscopy of Flour Fractions and Dough: Analysis of Spectral Differences and Potential to Improve Wheat Quality Prediction

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Spectroscopy of wheat kernels and flour has been used as a rapid tool to assess wheat quality, but predictions still lack in accuracy for most quality parameters except for protein content. To enable an improved prediction of further quality characteristics, new approaches are needed.
Denise Ziegler, Lukas Buck, Katharina Anne Scherf, Lutz Popper, Bernd Hitzmann   +4 more
wiley   +1 more source

Inactivation of Middle East respiratory syndrome coronavirus (MERS‐CoV) in plasma products using a riboflavin‐based and ultraviolet light‐based photochemical treatment

Transfusion, 2016
Middle East respiratory syndrome coronavirus (MERS‐CoV) has been identified as a potential threat to the safety of blood products. The Mirasol Pathogen Reduction Technology System uses riboflavin and ultraviolet (UV) light to render blood‐borne pathogens
S. Keil, R. Bowen, S. Marschner
semanticscholar   +1 more source

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2)

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical inhibition and genetic variation of the Breast Cancer Resistance Protein (BCRP/ABCG2) efflux transporter can significantly influence drug exposure, highlighting the need for reliable BCRP functional biomarkers. This study aimed to identify and evaluate biomarkers predictive of BCRP function in humans.
Andrew M. Riselli, Sook Wah Yee, Jia Yang, Claire M. Brett, Kelsey Trumbach, Xujia Zhou, Renmeng Liu, Xiaomin Liang, Yurong Lai, Runlan Huo, Yongjun Xue, Hong Shen, Lei Zhang, Xinning Yang, Qi Liu, Shiew‐Mei Huang, Kathleen M. Giacomini   +16 more
wiley   +1 more source

Interruptible demyelination in avian riboflavin deficient neuropathy

Cell & Bioscience
Background and aims The evolution of demyelination in individual internodes remains unclear although it has been noticed the paranodal demyelination precedes internodal demyelination in neuropathies with diverse aetiologies.
Zhao Cai
doaj   +1 more source

Recent Advances in Heterogenization of Photocatalysts on Polymer Supports and Applications in Organic Synthesis

ChemPhotoChem, EarlyView.
This review focuses on recent developments in heterogenization of photocatalysts into polymers, highlighting methods like photocatalyst polymerization, post‐grafting, and 3D printing. Discussion about these different approaches of heterogeneous photocatalysis (advantages and drawbacks) is provided.
Cloé Delacourt, Jean‐Philippe Goddard, Arnaud Spangenberg, Morgan Cormier   +3 more
wiley   +1 more source

Contribution of riboflavin supply pathways to Vibrio cholerae in different environments

Gut Pathogens, 2017
Background The waterborne diarrheagenic bacterium Vibrio cholerae, cause of the pandemic cholera disease, thrives in a variety of environments ranging from estuarine waters to the human intestinal tract.
Andrés Fuentes Flores, Ignacio Sepúlveda Cisternas, José Ignacio Vásquez Solis de Ovando, Alexia Torres, Víctor Antonio García-Angulo   +4 more
doaj   +1 more source

Bayes Factor Asymptotics for Variable Selection in the Gaussian Process Framework [PDF]

arXiv, 2018
Although variable selection is one of the most popular areas of modern statistical research, much of its development has taken place in the classical paradigm compared to the Bayesian counterpart. Somewhat surprisingly, both the paradigms have focussed almost completely on linear models, in spite of the vast scope offered by the model liberation ...
arxiv