Results 41 to 50 of about 69,663 (287)

Alteration of Riboflavin transporter expression in human cancer

open access: yes, 2022
Riboflavin (Rf), or vitamin B2, is an essential dietary component and represents the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are important enzymatic cofactors required for terminal mitochondrial metabolism ...
Maria Tolomeo   +4 more
core  

Riboflavin Lyase: An Intriguing Flavoenzyme Involved in Riboflavin Degradation [PDF]

open access: yes, 2020
Little is known about cofactor catabolism in the literature. Pyridoxamine, thiamin, heme and nicotinic acid degradation pathways are the only well-characterized catabolic pathways.
Chakrabarty, Yindrila
core  

Riboflavin Transporters RFVT/SLC52A Mediate Translocation of Riboflavin, Rather than FMN or FAD, across Plasma Membrane [PDF]

open access: yes, 2017
Riboflavin (vitamin B2) plays a role in various biochemical oxidation-reduction reactions. Flavin mononucleotide (FMN) and FAD, the biologically active forms, are made from riboflavin.
Yoshimatsu, Hiroki   +19 more
core   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

open access: yesAdvanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou   +11 more
wiley   +1 more source

Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]

open access: yes, 2010
Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Frans J. Kok   +15 more
core   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

open access: yesAdvanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng   +12 more
wiley   +1 more source

Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G-T mismatch

open access: yes, 2017
Riboflavin (vitamin B2) has been thought to be a promising antitumoral agent in photodynamic therapy, though the further application of the method was limited by the unclear molecular mechanism.
Wu, JS   +13 more
core   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li   +9 more
wiley   +1 more source

Riboflavin concentration in corneal stroma after intracameral injection [PDF]

open access: yesInternational Journal of Ophthalmology, 2015
AIM:To evaluate the enrichment of riboflavin in the corneal stroma after intracameral injection to research the barrier ability of the corneal endothelium to riboflavin in vivo.METHODS:The right eyes of 30 New Zealand white rabbits were divided into ...
Na Li   +5 more
doaj   +1 more source

Riboflavin [PDF]

open access: yes, 2020
Riboflavin is a water-soluble vitamin that must be acquired from the diet. Riboflavin uptake takes place through carrier-mediated absorption in the small intestine. Insight into human riboflavin transport and metabolism has expanded; currently, three inborn errors of riboflavin transport and metabolism are known. Riboflavin transporter deficiencies can
openaire   +3 more sources

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