Results 101 to 110 of about 13,344 (266)

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

open access: yesActa Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia   +4 more
wiley   +1 more source

Systematic Review Suggests Nutraceuticals Containing Vitamin B2 Could Provide an Alternative Treatment for Paediatric Migraines

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines. Methods This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic
Elisa Martello   +13 more
wiley   +1 more source

Structure‐based discovery of thiamine uptake inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel   +2 more
wiley   +1 more source

Coloured polyhydroxyalkanoates: A review

open access: yesColoration Technology, EarlyView.
Abstract Polyhydroxyalkanoates (PHAs) are a class of biopolymers produced by various microorganisms, with poly(3‐hydroxybutyrate) being the most extensively studied. PHAs are widely studied as substitutes for conventional plastics due to their similar physicochemical properties. However, the production cost of PHAs remains high.
Maria Luiza de Oliveira Zanini   +3 more
wiley   +1 more source

Engineering Intervertebral Disc Regeneration: Biomaterials, Cell Sources and Animal Models

open access: yesCell Proliferation, EarlyView.
This review highlights the current tissue engineering approaches utilising biomaterials, animal models and cell sources for intervertebral disc regeneration and discusses future opportunities. ABSTRACT Intervertebral disc (IVD) degeneration is an age‐related problem triggering chronic spinal issues, such as low back pain and IVD herniation.
Sidong Yang   +8 more
wiley   +1 more source

Variable treatment response in a patient with pyridoxal N phosphate oxidase (PNPO) deficiency- understanding the paradox

open access: yesEpilepsy & Behavior Reports, 2020
A 6-year-old girl presented with history of infantile onset epileptic encephalopathy and developmental delay. She had polymorphic seizures that were refractory to regular anti-seizure medication.
Smilu Mohanlal   +3 more
doaj  

Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism. [PDF]

open access: yesInt J Mol Sci, 2020
Mosegaard S   +5 more
europepmc   +1 more source

In vivo and in silico models of Drosophila for Parkinson's disease

open access: yesThe FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur   +3 more
wiley   +1 more source

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