Results 11 to 20 of about 917,291 (368)

Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease [PDF]

Nutrition & Metabolism
Background Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function.
Yanxian Wang, Xiangyu Bian, Min Wan, Weiyun Dong, Weina Gao, Zhanxin Yao, Changjiang Guo   +6 more
doaj   +3 more sources

Role of riboflavin deficiency in malaria pathophysiology [PDF]

PLOS Pathogens
The emergence of resistance against antimalarials and insecticides poses a significant threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria to identify new targets and alternative therapies. Malnutrition is a well-established risk factor for malaria. Deficiencies of micronutrients such as vitamin A, zinc,
Shweta Sharma, Arathy Ramachandran, Amit Sharma   +2 more
doaj   +4 more sources

Brown-Vialetto-Van Laere and Fazio Londe syndrome is associated with a riboflavin transporter defect mimicking mild MADD: a new inborn error of metabolism with potential treatment [PDF]

Orphanet Journal of Rare Diseases, 2010
We report on three patients (two siblings and one unrelated) presenting in infancy with progressive muscle weakness and paralysis of the diaphragm. Metabolic studies revealed a profile of plasma acylcarnitines and urine organic acids suggestive of a mild
Alida E. M. Stroomer, AN Spaan, Annet M. Bosch, C Antozzi, CD Capo-chichi, Frits A. Wijburg, FV Ventura, Gepke Visser, Hans R. Waterham, Hennie Knoester, HJ Powers, JL Hove Van, Lodewijk IJlst, Marinus Duran, N Gregersen, Nico G. G. M. Abeling, RK Olsen, Ronald J. Wanders, RT Leshner, S Dipti, S Sathasivam, S Yamamoto, SI Goodman, V Tiranti, W. Ludo van der Pol, WJ Rhead   +25 more
core   +9 more sources

Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism. [PDF]

Int J Mol Sci, 2020
As an essential vitamin, the role of riboflavin in human diet and health is increasingly being highlighted. Insufficient dietary intake of riboflavin is often reported in nutritional surveys and population studies, even in non-developing countries with ...
Mosegaard S, Dipace G, Bross P, Carlsen J, Gregersen N, Olsen RKJ.   +5 more
europepmc   +2 more sources

Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice. [PDF]

Sci Rep, 2020
Riboflavin transporter 3 (RFVT3), encoded by the SLC52A3 gene, is important for riboflavin homeostasis in the small intestine, kidney, and placenta. Our previous study demonstrated that Slc52a3 knockout (Slc52a3−/−) mice exhibited neonatal lethality and ...
Jin C, Yonezawa A, Yoshimatsu H, Imai S, Koyanagi M, Yamanishi K, Nakagawa S, Itohara K, Omura T, Nakagawa T, Nagai J, Matsubara K.   +11 more
europepmc   +2 more sources

Premature farrowing and stillbirths in two organic sow farms due to riboflavin deficiency [PDF]

Porcine Health Management, 2023
Background Riboflavin deficiency can lead to premature farrowing, stillborn piglets, weak-born piglets and neonatal death. Riboflavin (vitamin B2) is considered essential for reproductive function. The longer the period on riboflavin-deficient diets, the
Camilla Torreggiani, Dominiek Maes, Luigi Franchi, Valeria Raffi, Elena Borri, Alice Prosperi, Chiara Chiapponi, Andrea Luppi   +7 more
doaj   +2 more sources

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis [PDF]

Redox Biology, 2022
Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha, Larissa Ikelle, Mustafa S. Makia, Ryan Crane, Xue Zhao, Mashal Kakakhel, Muayyad R. Al-Ubaidi, Muna I. Naash   +7 more
doaj   +2 more sources

Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells. [PDF]

Sci Rep, 2017
Riboflavin deficiency is widespread in many regions over the world, especially in underdeveloped countries. In this study, we investigated the effects of riboflavin deficiency on protein expression profiles in HepG2 cells in order to provide molecular ...
Xin Z, Pu L, Gao W, Wang Y, Wei J, Shi T, Yao Z, Guo C.   +7 more
europepmc   +2 more sources

Riboflavin Attenuates Influenza Virus Through Cytokine-Mediated Effects on the Diversity of the Gut Microbiota in MAIT Cell Deficiency Mice

Frontiers in Microbiology, 2022
Influenza is a serious respiratory disease that continues to threaten global health. Mucosa-associated invariant T (MAIT) cells use T-cell receptors (TCRs) that recognize microbial riboflavin derived intermediates presented by the major ...
Ying Li, Ying Li, Ying Li, Ying Li, Chun-Wei Shi, Chun-Wei Shi, Chun-Wei Shi, Chun-Wei Shi, Yu-Ting Zhang, Yu-Ting Zhang, Yu-Ting Zhang, Yu-Ting Zhang, Hai-Bin Huang, Hai-Bin Huang, Hai-Bin Huang, Hai-Bin Huang, Yan-Long Jiang, Yan-Long Jiang, Yan-Long Jiang, Yan-Long Jiang, Jian-Zhong Wang, Jian-Zhong Wang, Jian-Zhong Wang, Jian-Zhong Wang, Xin Cao, Xin Cao, Xin Cao, Xin Cao, Nan Wang, Nan Wang, Nan Wang, Nan Wang, Yan Zeng, Yan Zeng, Yan Zeng, Yan Zeng, Gui-Lian Yang, Gui-Lian Yang, Gui-Lian Yang, Gui-Lian Yang, Wen-Tao Yang, Wen-Tao Yang, Wen-Tao Yang, Wen-Tao Yang, Chun-Feng Wang, Chun-Feng Wang, Chun-Feng Wang, Chun-Feng Wang   +47 more
doaj   +2 more sources

Riboflavin Deficiency in Rats Decreases de novo Formate Production but Does Not Affect Plasma Formate Concentration. [PDF]

J Nutr, 2017
Background: The one-carbon metabolism pathway is highly dependent on a number of B vitamins in order to provide one-carbon units for purine and thymidylate biosynthesis as well as homocysteine remethylation.
MacMillan L, Lamarre SG, daSilva RP, Jacobs RL, Brosnan ME, Brosnan JT.   +5 more
europepmc   +2 more sources