Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Reductive Methylation: An Alternative to Lysine → Arginine Mutagenesis. [PDF]
Molina OJ +4 more
europepmc +1 more source
RNase A is inhibited by the cysteine-rich protein thionein but not by the metal-containing form metallothionein. [PDF]
Trujillo-González F +4 more
europepmc +1 more source
Mechanism of Action of Bovine Pancreatic Ribonuclease [PDF]
A, Deavin, A P, Mathias, B R, Rabin
openaire +3 more sources
Anfinsen Redux: Ribonuclease Folding in the Single-Molecule Regime. [PDF]
Melkonian AV +3 more
europepmc +1 more source
Therapeutic Potential of Deferiprone-Resveratrol Hybrid (DFP-RVT) Against Hepatic Iron Overload in β-Thalassemia Mice: A Proteomic Analysis. [PDF]
Maneekesorn S +11 more
europepmc +1 more source
Pan-Cancer Analysis Reveals Ribonuclease K (RNASEK) as a Potential Prognostic Biomarker in Pancreatic Cancer and a Diagnostic Indicator Across Multiple Human Cancers. [PDF]
Hassan Elsheikh NA +4 more
europepmc +1 more source
ZC3H12A: A Critical Mediator of Inflammation, Tumor Immunotherapy, and Metabolic-Immune Crosstalk-Implications for Disease Treatment. [PDF]
Lu M, Guo J, Wang C, Wan B, Ma T.
europepmc +1 more source
Non-enzymatic Rnaseh2c orchestrates proliferating macrophage-driven immunosuppression and HCC progression via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8<sup>+</sup> T<sub>ex</sub> infiltration: a novel therapeutic paradigm with "Rnaseh2c-In1" inhibitor. [PDF]
Wang Z +9 more
europepmc +1 more source

