Results 111 to 120 of about 12,408 (251)
"Plasma"-type ribonuclease in pancreatic cancer diagnosis: a critical appraisal.
, 1981 The so-called "plasma" ribonuclease (RNase), described as increased in most patients with pancreatic cancer, was studied in the blood of 92 subjects utilizing the method of Reddi and Holland, to evaluate its reliability in detecting pancreatic tumors.
FABRIS C. +4 more
core
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
MedComm, Volume 7, Issue 7, July 2026.Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source
A comparison of leaf and pancreatic ribonuclease [PDF]
, 1955 Pirie, N. W., Margaret Holden
core +1 more source
Tests of predictions made by the Equilibrium Model for the effect of temperature on enzyme activity
, 2008 The Classical Model describing the effects of temperature on enzyme activity consists of two processes: the catalytic reaction defined by ΔG cat and irreversible inactivation defined by ΔG inact, this model however, does not account for the observed ...
Oudshoorn, Matthew Leslie
core
The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer
Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli +1 more
wiley +1 more source
Degradation of DNA-RNA Hybrids by Aggregates of Pancreatic Ribonuclease
, 1975 Evidence has been obtained that dimers and higher aggregates of pancreatic ribonuclease arlready known as capable of degrading double stranded RNAs, are also able to degrade a DNA-RNA hybrid.
Libonati M. +4 more
core
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.GR‐A knockin mice were generated that express the classic full‐length glucocorticoid receptor (GR‐A) but lack the highly conserved translational isoforms GR‐B, GR‐C1, GR‐C2, GR‐C3, GR‐D1, GR‐D2, and GR‐D3 that have progressively shorter N‐terminal transactivation domains (NTDs).
Robert H. Oakley +8 more
wiley +1 more source
, 2016 Ribonucleases represent a new class of antitumor RNA-damaging drugs. However, many wild-type members of the vertebrate secreted ribonuclease family are not cytotoxic because they are not able to evade the cytosolic ribonuclease inhibitor.
Benito i Mundet, Antoni +4 more
core +1 more source
FEBS Open Bio, Volume 16, Issue 6, Page 1115-1131, June 2026.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source