Results 171 to 180 of about 475,848 (256)

The return of pancreatic ribonucleases

Trends in Biochemical Sciences, 1989
A decade after losing favor as an 'uninteresting' digestive enzyme, pancreatic ribonuclease has been found to be homologous to a series of extracellular proteins that may influence tumor cell growth, neurological development and biological differentiation.
S A, Benner, R K, Allemann
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The interaction of DNA with pancreatic ribonuclease A

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
Abstract 1. 1. The complex formation of calf thymus DNA with pancreatic ribonuclease A (ribonucleate pyrimidinenucleotido-2′-transferase (cycling), EC 2.7.7.16) was studied through ultracentrifugation, competitive inhibition of ribonuclease activity and gel filtration on Sephadex G-200.
H, Sekine, E, Nakano, K, Sakaguchi
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Crystallization of mouse pancreatic ribonuclease

Journal of Molecular Biology, 1988
Mouse pancreatic ribonuclease has been crystallized in a form suitable for X-ray structure determination. The crystals grown from solutions of 2-methyl-2,4-pentanediol diffract to high resolution and belong to the hexagonal space group P6(1) (P6(5)) with unit cells dimensions a = b = 64.44 A, c = 53.91 A, y = 120 degrees and V = 1.94 x 10(5) A3 (1 A ...
A L, Perry, R A, Palmer
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Immunologic comparison of pancreatic ribonucleases

Immunochemistry, 1976
Abstract Ouchterlony double immunodiffusion and micro-complement fixation were used in cross-reactivity studies with 9 pancreatic ribonucleases differing 3–28% in amino acid sequence and rabbit antisera to cow, gnu, reindeer and whale ribonuclease.
WELLING, Gjalt W., Groen, G., Beintema, Jaap J., Emmens, Marchienus, Schröder, F.P.   +4 more
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The molecular evolution of pancreatic ribonuclease

Journal of Molecular Evolution, 1977
The primary structures of pancreatic ribonucleases from 26 species (18 artiodactyls, horse, whale, 5 rodents and turtle) are known. Several species contain identical ribonucleases (cow/bison; sheep/goat), other species show polymorphism (arabian camel) or the presence of two structural gene loci (guinea pig pancreas contains two ribonucleases that ...
Beintema, Jaap J., Gaastra, Wim, Lenstra, Johannes A., Welling, Gjalt W., Fitch, Walter M.   +4 more
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Ribonuclease of bovine milk: Serological relationship to pancreatic ribonuclease

Archives of Biochemistry and Biophysics, 1964
Abstract Ribonuclease isolated from bovine milk has been shown to be serologically identical to pancreatic ribonuclease. The presence of ribonuclease in milk was demonstrated directly by a gel-diffusion method. The serological method employed did not detect ribonuclease in bovine serum.
E J, COULSON, H, STEVENS
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Pancreatic Ribonuclease Distribution and Comparisons in Mammals

Nature New Biology, 1973
PANCREATIC RNAase is absent or present in very small amounts in the pancreas of species such as man, cat, seal and rabbit1. Likewise no RNAase activity has been found in the pancreatic juice of dog by Marchis-Mouren et al.2 and in the juice of cat and rabbit by Berndt3.
BEINTEMA, JJ, SCHEFFER, AJ, VANDIJK, H, WELLING, GW, ZWIERS, H   +4 more
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Biological Function of Pancreatic Ribonuclease

Nature, 1969
The physiological function of this much studied pancreatic enzyme has been misunderstood. It is essential only in ruminants and certain other herbivores, where it has a special function.
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Antigenic reactivity of artiodactyl pancreatic ribonucleases with antiserum to cow ribonuclease A

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1976
Abstract The antigenecity of six pancreatic ribonucleases differing up to 11% in amino acid sequence, and of a synthetic cow ribonuclease fragment (residues 1–14) was determined with antiserum to cow ribonuclease A, using the modified phage technique.
WELLING, GW, GROEN, G
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Human pancreatic ribonuclease 1

Cancer, 2000
Human pancreatic ribonuclease (RNase 1) is a pancreatic enzyme that is present at high levels in the serum of most patients with pancreatic adenocarcinoma. For this reason, the authors studied its patterns of expression at the single-cell level in pancreatic adenocarcinoma tissues by immunohistochemical analysis and in situ hybridization (ISH ...
R, Peracaula, K R, Cleary, J, Lorenzo, R, de Llorens, M L, Frazier   +4 more
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