Insulin Signalling‐Inducible IFITM1 Promotes Multiple Myeloma Progression and Bortezomib Resistance
ABSTRACT Insulin substantially promotes the growth of malignant cells that overexpress the insulin receptor (INSR), and insulin excess has been recognised as a cancer‐promoting factor in patients. Interferon‐induced transmembrane protein 1 (IFITM1) is also overexpressed in various cancers.
Ji‐Young Lim +4 more
wiley +1 more source
Identification of a Novel Intracellular Function of the Secreted Ribonuclease RNASE1 in Inhibiting Gene Expression. [PDF]
Singh R +10 more
europepmc +1 more source
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Meng Xu +6 more
wiley +1 more source
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
R. Johnson +4 more
semanticscholar +1 more source
Advances in antisense oligonucleotide treatment for cancer. [PDF]
Zhu L, Muhtar P, Goyama S, Yoshimi A.
europepmc +1 more source
Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Pseudouridine residues as substrates for serum ribonucleases. [PDF]
Gutierrez CS +5 more
europepmc +1 more source
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid +13 more
wiley +1 more source
<i>AKT2</i> Exon 3 Variants and Their Prevalence in Prostate Cancer Patients: Insights from a Jordanian Clinical Cohort. [PDF]
Rahahlah N +8 more
europepmc +1 more source
Omnivore RNA pyrophosphatase: a versatile enzyme that efficiently removes diverse protecting groups from the 5' end of RNA. [PDF]
Ingle S, Belasco JG.
europepmc +1 more source

