Results 41 to 50 of about 156,401 (384)

On the Stabilization of Ribonuclease S-Protein by Ribonuclease S-Peptide

open access: yesJournal of Biological Chemistry, 1969
Abstract Rapid "scrambling" of the disulfide bonds of RNase S-protein, with concomitant inactivation of potential RNase activity, occurs during catalysis by the disulfide interchange enzyme of microsomes. RNase S-peptide prevents this interchange reaction.
Christian B. Anfinsen, Ikunoshin Kato
openaire   +3 more sources

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti‐inflammatory and cardioprotective
Eike Kleinert   +15 more
doaj   +1 more source

The Secreted Ribonuclease SRE1 Contributes to Setosphaeria turcica Virulence and Activates Plant Immunity

open access: yesFrontiers in Microbiology, 2022
During the plant infection process, pathogens can secrete several effectors. Some of the effectors are well-known for their roles in regulating plant immunity and promoting successful pathogen colonization.
Shidao He   +6 more
doaj   +1 more source

Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Although MARF1 (meiosis regulator and mRNA stability factor 1) is an ancient protein, identification of its function in mammalian female germ cell development and fertility is recent.
Qingqing Yao   +13 more
semanticscholar   +1 more source

Generation of 2′,3′-Cyclic Phosphate-Containing RNAs as a Hidden Layer of the Transcriptome

open access: yesFrontiers in Genetics, 2018
Cellular RNA molecules contain phosphate or hydroxyl ends. A 2′,3′-cyclic phosphate (cP) is one of the 3′-terminal forms of RNAs mainly generated from RNA cleavage by ribonucleases.
Megumi Shigematsu   +2 more
doaj   +1 more source

RNase A does not translocate the alpha-hemolysin pore. [PDF]

open access: yesPLoS ONE, 2014
The application of nanopore sensing utilizing the α-hemolysin pore to probe proteins at single-molecule resolution has expanded rapidly. In some studies protein translocation through the α-hemolysin has been reported. However, there is no direct evidence,
Besnik Krasniqi, Jeremy S Lee
doaj   +1 more source

Origin, Diversity, and Multiple Roles of Enzymes with Metallo-β-Lactamase Fold from Different Organisms

open access: yesCells, 2023
β-lactamase enzymes have generated significant interest due to their ability to confer resistance to the most commonly used family of antibiotics in human medicine.
Seydina M. Diene   +8 more
doaj   +1 more source

Ribonuclease selection for ribosome profiling

open access: yesNucleic Acids Research, 2016
Ribosome profiling has emerged as a powerful method to assess global gene translation, but methodological and analytical challenges often lead to inconsistencies across labs and model organisms.
Maxim V. Gerashchenko, V. Gladyshev
semanticscholar   +1 more source

Genomic function during the lampbrush chromosome stage of amphibian oogenesis [PDF]

open access: yes, 1966
Throughout its lengthy developmental history the disposition of the genetic material in the amphibian oocyte nucleus differs from that in other cell types.
Crippa, Marco   +3 more
core   +1 more source

Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita.

open access: yesJournal of Clinical Investigation, 2015
Dyskeratosis congenita (DC) and related syndromes are inherited, life-threatening bone marrow (BM) failure disorders, and approximately 40% of cases are currently uncharacterized at the genetic level.
H. Tummala   +12 more
semanticscholar   +1 more source

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