Results 51 to 60 of about 49,990 (134)

Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors [PDF]

, 2016
We analyzed a multi-drug resistant (MR) HIV-1 re- verse transcriptase (RT), subcloned from a patient- derived subtype CRF02 AG, harboring 45 amino acid exchanges, amongst them four thymidine analog mutations (TAMs) relevant for high-level AZT (azi-
Bodem, Jochen, Buchholz, Bernd, Corona, Angela, Di Santo, Roberto, Jordan, Mareike, Maccioni, Elias, Schneider, Anna, Spã¶ring, Imke, Tramontano, Enzo, Wã¶hrl, Birgitta M.   +9 more
core   +1 more source

A possible mechanism for cold denaturation of proteins at high pressure [PDF]

, 2003
We study cold denaturation of proteins at high pressures. Using multicanonical Monte Carlo simulations of a model protein in a water bath, we investigate the effect of water density fluctuations on protein stability. We find that above the pressure where
A. Hansen, A. Trovato, B. L. Chen, B. L. Chen, B. Lee, C -J. Tsai, C. N. Pace, C. Vanderzande, D. Chandler, E. Paci, F. H. Stillinger, G. Caldarelli, G. Hummer, G. P. Privalov, G. Panick, G. W. Robinson, H. Ludwing, H. S. Chan, H. S. Frank, J. Jonas, J. Zhang, J. Zipp, K. A. Dill, K. A. Dill, K. A. Dill, K. A. Dill, K. A. T. Silverstein, K. C. Cho, K. F. Lau, L. R. Pratt, L. Smeller, M. W. Mahoney, N. Muller, O. Collet, P. Bruscolini, P. L. Privalov, P. L. Privalov, P. R. ten Wolde, P. R. ten Wolde,, R. A. Pierotti, S. A. Hawley, S. A. Hawley, S. Chan, S. J. Gill, S. Kunugi, S. Shimizu, S. Shimizu, V. A. Payne, V. F. Petrenko, W. Kauzmann, Y. Nozaki   +50 more
core   +3 more sources

Understanding diversity of human innate immunity receptors: analysis of surface features of leucine-rich repeat domains in NLRs and TLRs. [PDF]

, 2009
BackgroundThe human innate immune system uses a system of extracellular Toll-like receptors (TLRs) and intracellular Nod-like receptors (NLRs) to match the appropriate level of immune response to the level of threat from the current environment.
Godzik, Adam, Istomin, Andrei Y
core   +4 more sources

Ribonuclease H Levels during the Response of Bovine Lymphocytes to Concanavalin A [PDF]

, 1977
W. Büsen, J. Hinrich Peters, Peter Hausen   +2 more
openalex   +1 more source

Development of a new class of chemical and biological ultrasensors: Ribonuclease contamination and control [PDF]

In order to define ribonuclease contamination, an assay for ribonuclease having picogram level sensitivity was established. In this assay, polycytidylic acid is digested by ribonuclease leading to smaller fragments of poly C that remain soluble after ...

core   +1 more source

Mechanistic Independence of Avian Myeloblastosis Virus DNA Polymerase and Ribonuclease H [PDF]

, 1974
Lorraine C. Brewer, Robert D. Wells
openalex   +1 more source

RNA‐Dependent DNA polymerase and ribonuclease H from Friend virions [PDF]

, 1974
B. J. Weimann, J Schmidt, Dirk I. Wolfrum   +2 more
openalex   +1 more source

Low‐temperature ¹H‐NMR evidence of the folding of isolated ribonuclease S‐peptide [PDF]

, 1983
M. Rico, José Luís Corchero, J. Santoro, F. J. Bermejo, Javier Herranz, E. Gallego   +5 more
openalex   +1 more source

Molecular cloning of a ribonuclease H (RNase HI) gene from an extreme thermophileThermus thermophilusHB8: a thermostable RNase H can functionally replace theEscherichia colienzymein vivo [PDF]

, 1991
Mitsuhiro Itaya, Kanae Kondo
openalex   +1 more source

Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells [PDF]

, 1995
Richard V. Giles, Carolyn J. Ruddell, David G. Spiller, John A. Green, D M Tidd   +4 more
openalex   +1 more source