Results 161 to 170 of about 19,244,439 (340)
Multiplexed in-gel microfluidic immunoassays: characterizing protein target loss during reprobing of benzophenone-modified hydrogels. [PDF]
, 2019 From whole tissues to single-cell lysate, heterogeneous immunoassays are widely utilized for analysis of protein targets in complex biospecimens. Recently, benzophenone-functionalized hydrogel scaffolds have been used to immobilize target protein for ...
Gopal, Anjali, Herr, Amy E
core +1 more source
The RNA Subunit of Ribonuclease P from the Zebrafish, Danio rerio [PDF]
, 1996 Paul S. Eder +3 more
openalex +1 more source
Advanced Materials, EarlyView.Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi +8 more
wiley +1 more source
Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork [PDF]
, 2017 Jackson, Jessica +5 more
core +2 more sources
Protein folding tames chaos [PDF]
, 2013 Protein folding produces characteristic and functional three-dimensional structures from unfolded polypeptides or disordered coils. The emergence of extraordinary complexity in the protein folding process poses astonishing challenges to theoretical ...
Wei, Guo-Wei, Xia, Kelin
core
Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA [PDF]
, 2000 Daniel N. Frank +4 more
openalex +1 more source
Advanced Materials, EarlyView.Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim +6 more
wiley +1 more source
Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme [PDF]
, 2000 Eric L. Christian +2 more
openalex +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Zoonotic DiseasesThe human coronavirus 229E (HCoV-229E) is a member of the human coronavirus family that includes SARS-CoV-2, the causative agent of COVID-19. Developing antiviral strategies and compounds is crucial to treat and prevent HCoV-229E infections and the ...
Yujun Liu +3 more
doaj +1 more source