Results 241 to 250 of about 19,244,439 (340)

Function and subnuclear distribution of Rpp21, a protein subunit of the human ribonucleoprotein ribonuclease P [PDF]

, 2001
Nayef Jarrous, Robert C. Reiner, Donna Wesolowski, Hagit Mann, Cecilia Guerrier-Takada, Sidney Altman   +5 more
openalex   +1 more source

Capsaicin Alleviates Autophagy‐Lysosomal Dysfunction via PPARA‐Mediated V‐ATPase Subunit ATP6V0E1 Signaling in 3xTg‐AD Mice

Advanced Science, EarlyView.
Capsaicin enhances lipid metabolism, reduces lipid deposition, and alleviates AD‐related pathologies. Capsaicin activates PPARA, promoting the expression of PPAR signaling pathway‐related genes and accelerating lipid metabolism. Capsaicin upregulates ATP6V0E1‐V‐ATPase‐mediated lysosomal acidification, enhancing lipid droplet clearance. PPARA is the key
Haitao Yu, Jia Chen, Fangzhou Wang, Dongdong Jia, Shuguang Bi, Yuming Mao, Yu‐qi Zhang, Tian‐long Gao, Liu Yang, Jia‐xu Du, Zi‐han Zhou, Xi‐Chen Zhu, Gao‐shang Chai   +12 more
wiley   +1 more source

Formation of mitochondria of locusta migratoria flight muscle [PDF]

, 1971
Boardman, N. K., Bücher, Theodor, Kleinow, Walter, Linnane, Anthony W., Neupert, Walter, Sebald, Walter, Smillie, R. M.   +6 more
core   +1 more source

Hyperprocessing reaction of tRNA by Bacillus subtilis ribonuclease P ribozyme [PDF]

, 2001
Yoshiaki Hori, Etsuko Sakai, Terumichi Tanaka, Yo Kikuchi   +3 more
openalex   +1 more source

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Advanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan, Chun‐Miao Deng, Lin Tang, Shu‐Jun Li, Tao‐Yang Xu, Xian Wei, Xin‐Yi Zhang, Can‐Can Zheng, Li Deng, Cui Shao, Zhong‐Min Ouyang, Alfred King‐Yin Lam, Rong Zhang, Jun Liu, Xing‐Yuan Shi, Zhen‐Yu Pan, Wei Dai, Ming‐Liang He, Simon Law, Xu Li, Xiao‐Bing Chen, Cheng Zhou, Bin Li, Wen‐Wen Xu   +23 more
wiley   +1 more source

Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin‐9/Rab6A‐Mediated Trafficking of c‐Mpl in MKs

Advanced Science, EarlyView.
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao, Huixian Ma, Guosheng Li, Jilong Xiao, Zhiyu Shi, Mingying Li, Xinguang Liu, Tao Sun, Chunyan Ji   +8 more
wiley   +1 more source

Eukaryotic ribonuclease P: Increased complexity to cope with the nuclear pre-tRNA pathway [PDF]

, 2001
Shaohua Xiao, Felicia Houser‐Scott, David R. Engelke   +2 more
openalex   +1 more source

Protein-precursor tRNA contact leads to sequence-specific recognition of 5' leaders by bacterial ribonuclease P.

Journal of Molecular Biology, 2010
Kristin S. Koutmou, N. Zahler, J. Kurz, F. Campbell, M. Harris, C. Fierke   +5 more
semanticscholar   +1 more source

Cleavage of Bipartite Substrates by Rice and Maize Ribonuclease P. Application to Degradation of Target mRNAs in Plants [PDF]

, 2001
M. L. Stephen Raj, Dileep K. Pulukkunat, James F. Reckard, George Thomas, Venkat Gopalan   +4 more
openalex   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu, Han Li, Shuang‐feng Zi, Ying Tang, Na Liu, Ke‐xin Li, Shi‐ke Geng, Hui‐qing Lu, Zhi‐kang Xie, Xin‐yi Xu, Yi‐ting Wei, Li‐xin Wang, Tao Liu, Jie Chao, Yi Yang, Hai‐bo Qiu, Wei Huang, Ling Liu   +17 more
wiley   +1 more source