Results 31 to 40 of about 52,696 (181)

Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways.

open access: yesPLoS Genetics, 2023
Metabolic pathways are known to sense the environmental stimuli and result in physiological adjustments. The responding processes need to be tightly controlled. Here, we show that upon encountering P. aeruginosa, C.
Yi-Ting Tsai   +2 more
doaj   +1 more source

Modular Architecture of Bacterial RNase P Ribozymes as a Structural Platform for RNA Nanostructure Design

open access: yesCHIMIA, 2018
Ribonuclease P (RNase P) is a class of enzymes involved in the processing of precursor tRNAs to remove their 5'-leader sequences. Ribonuclease P enzymes are classified into two completely distinct classes, i.e.
Yuri Nozawa   +3 more
doaj   +1 more source

A Novel Method to Isolate RNase MRP Using RNA Streptavidin Aptamer Tags

open access: yesBio-Protocol, 2023
Interactions between RNA-binding proteins and RNA molecules are at the center of multiple biological processes. Therefore, accurate characterization of the composition of ribonucleoprotein complexes (RNPs) is crucial.
Violette Charteau   +2 more
doaj   +1 more source

Microbial identification by mass cataloging

open access: yesBMC Bioinformatics, 2006
Background The public availability of over 180,000 bacterial 16S ribosomal RNA (rRNA) sequences has facilitated microbial identification and classification using hybridization and other molecular approaches.
Fox George E   +3 more
doaj   +1 more source

3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis

open access: yesMolecules, 2020
Initiation of protein-primed (-) strand DNA synthesis in hepatitis B virus (HBV) requires interaction of the viral reverse transcriptase with epsilon (ε), a cis-acting regulatory signal located at the 5’ terminus of pre-genomic RNA (pgRNA), and several ...
Ellen Bak   +6 more
doaj   +1 more source

Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA. [PDF]

open access: yesGenes & Development, 1994
The polycistronic mRNA of the histidine operon is subject to a processing event that generates a rather stable transcript encompassing the five distal cistrons. The molecular mechanisms by which such a transcript is produced were investigated in Escherichia coli strains carrying mutations in several genes for exo- and endonucleases.
ALIFANO, Pietro   +5 more
openaire   +6 more sources

Structure and mechanistic features of the prokaryotic minimal RNase P

open access: yeseLife, 2021
Endonucleolytic removal of 5’-leader sequences from tRNA precursor transcripts (pre-tRNAs) by ribonuclease P (RNase P) is essential for protein synthesis.
Rebecca Feyh   +7 more
doaj   +1 more source

Structure and Function of Eukaryotic Ribonuclease P RNA [PDF]

open access: yesMolecular Cell, 2006
Ribonuclease P (RNase P) is the ribonucleoprotein endonuclease that processes the 5' ends of precursor tRNAs. Bacterial and eukaryal RNase P RNAs had the same primordial ancestor; however, they were molded differently by evolution. RNase P RNAs of eukaryotes, in contrast to bacterial RNAs, are not catalytically active in vitro without proteins.
Donald Evans   +3 more
openaire   +3 more sources

Comparative analysis of ribonuclease P RNA of the planctomycetes [PDF]

open access: yesInternational Journal of Systematic and Evolutionary Microbiology, 2004
The planctomycetes, order Planctomycetales, are a distinct phylum of domain Bacteria. Genes encoding the RNA portion of ribonuclease P (RNase P) of some planctomycete members were sequenced and compared with existing database planctomycete sequences.
Butler, Margaret K., Fuerst, John A.
openaire   +4 more sources

Cloning, expression and location of RNase9 in human epididymis

open access: yesBMC Research Notes, 2008
Background Mammalian spermatozoa become fully motile and fertile during transit through the luminal fluid of the epididymis. At least 200 proteins are present in the epididymal lumen, but the potential roles of these luminal proteins in male fertility ...
Lin YQ   +7 more
doaj   +1 more source

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