Results 31 to 40 of about 331,224 (206)

Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways.

open access: yesPLoS Genetics, 2023
Metabolic pathways are known to sense the environmental stimuli and result in physiological adjustments. The responding processes need to be tightly controlled. Here, we show that upon encountering P. aeruginosa, C.
Yi-Ting Tsai   +2 more
doaj   +1 more source

A Novel Method to Isolate RNase MRP Using RNA Streptavidin Aptamer Tags

open access: yesBio-Protocol, 2023
Interactions between RNA-binding proteins and RNA molecules are at the center of multiple biological processes. Therefore, accurate characterization of the composition of ribonucleoprotein complexes (RNPs) is crucial.
Violette Charteau   +2 more
doaj   +1 more source

Modular Architecture of Bacterial RNase P Ribozymes as a Structural Platform for RNA Nanostructure Design

open access: yesCHIMIA, 2018
Ribonuclease P (RNase P) is a class of enzymes involved in the processing of precursor tRNAs to remove their 5'-leader sequences. Ribonuclease P enzymes are classified into two completely distinct classes, i.e.
Yuri Nozawa   +3 more
doaj   +1 more source

3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis

open access: yesMolecules, 2020
Initiation of protein-primed (-) strand DNA synthesis in hepatitis B virus (HBV) requires interaction of the viral reverse transcriptase with epsilon (ε), a cis-acting regulatory signal located at the 5’ terminus of pre-genomic RNA (pgRNA), and several ...
Ellen Bak   +6 more
doaj   +1 more source

Bistability of an In Vitro Synthetic Autoregulatory Switch [PDF]

open access: yesACS Synthetic Biology 2012, 2011
The construction of synthetic biochemical circuits is an essential step for developing quantitative understanding of information processing in natural organisms. Here, we report construction and analysis of an in vitro circuit with positive autoregulation that consists of just four synthetic DNA strands and three enzymes, bacteriophage T7 RNA ...
arxiv   +1 more source

Microbial identification by mass cataloging

open access: yesBMC Bioinformatics, 2006
Background The public availability of over 180,000 bacterial 16S ribosomal RNA (rRNA) sequences has facilitated microbial identification and classification using hybridization and other molecular approaches.
Fox George E   +3 more
doaj   +1 more source

Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA. [PDF]

open access: yesGenes & Development, 1994
The polycistronic mRNA of the histidine operon is subject to a processing event that generates a rather stable transcript encompassing the five distal cistrons. The molecular mechanisms by which such a transcript is produced were investigated in Escherichia coli strains carrying mutations in several genes for exo- and endonucleases.
ALIFANO, Pietro   +5 more
openaire   +6 more sources

Structure and mechanistic features of the prokaryotic minimal RNase P

open access: yeseLife, 2021
Endonucleolytic removal of 5’-leader sequences from tRNA precursor transcripts (pre-tRNAs) by ribonuclease P (RNase P) is essential for protein synthesis.
Rebecca Feyh   +7 more
doaj   +1 more source

Structure and Function of Eukaryotic Ribonuclease P RNA [PDF]

open access: yesMolecular Cell, 2006
Ribonuclease P (RNase P) is the ribonucleoprotein endonuclease that processes the 5' ends of precursor tRNAs. Bacterial and eukaryal RNase P RNAs had the same primordial ancestor; however, they were molded differently by evolution. RNase P RNAs of eukaryotes, in contrast to bacterial RNAs, are not catalytically active in vitro without proteins.
Donald Evans   +3 more
openaire   +3 more sources

Evaluation of the allergenicity potential of TcPR-10 protein from Theobroma cacao. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: The pathogenesis related protein PR10 (TcPR-10), obtained from the Theobroma cacao-Moniliophthora perniciosa interaction library, presents antifungal activity against M. perniciosa and acts in vitro as a ribonuclease.
Sara Pereira Menezes   +8 more
doaj   +1 more source

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