Results 61 to 70 of about 331,224 (206)

High sensitivity-low cost detection of SARS-CoV-2 by two steps end point RT-PCR with agarose gel electrophoresis visualization

open access: yesScientific Reports, 2021
More than one year since Coronavirus disease 2019 (COVID-19) pandemic outbreak, the gold standard technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection is still the RT-qPCR.
Solange Figueroa   +6 more
doaj   +1 more source

The pointed $p$-groups on a block algebra [PDF]

open access: yesarXiv, 2023
A pointed $p$-group is a pointed group $P_\gamma$ such that $P$ is a $p$-group. We parameterize the pointed $p$-groups on a group algebra or on a block algebra of a group algebra. The parameterization involves $p$-subgroups and irreducible characters of centralizers of $p$-subgroups.
arxiv  

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

open access: yesBMC Cell Biology, 2009
Background Parathyroid hormone (PTH) gene expression is regulated post-transcriptionally through the binding of the trans-acting proteins AU rich binding factor 1 (AUF1), Upstream of N-ras (Unr) and KH-type splicing regulatory protein (KSRP) to an AU ...
Schoenberg Daniel R   +6 more
doaj   +1 more source

Multiple RNA processing defects and impaired chloroplast function in plants deficient in the organellar protein-only RNase P enzyme. [PDF]

open access: yesPLoS ONE, 2015
Transfer RNA (tRNA) precursors undergo endoribonucleolytic processing of their 5' and 3' ends. 5' cleavage of the precursor transcript is performed by ribonuclease P (RNase P).
Wenbin Zhou   +5 more
doaj   +1 more source

The Multiple Substrate Recognition Properties of Ribonuclease P [PDF]

open access: yesBiophysical Journal, 2012
Ribonuclease P is an essential enzyme that is responsible for catalyzing the 5’end maturation of transfer RNA. In Bacteria, the RNase P holoenzyme is composed of a large RNA (∼400nt) and a smaller (∼100aa) protein. RNase P RNA contains the enzyme active site and interacts with tRNA; however, the protein subunit is essential in vivo because it binds the
Lindsay E. Yandek   +4 more
openaire   +2 more sources

Assessing site-specific enhancements imparted by hyperpolarized water in folded and unfolded proteins by 2D HMQC NMR [PDF]

open access: yesarXiv, 2020
Hyperpolarized water can be a valuable aid in protein NMR, leading to amide group 1H polarizations that are orders of magnitude larger than their thermal counterparts. Suitable procedures can exploit this to deliver 2D 1H-15N correlations with good resolution and enhanced sensitivity.
arxiv  

Tertiary structure prediction of C-peptide of ribonuclease A by multicanonical algorithm [PDF]

open access: yesJ. Phys. Chem. B 102 (1998) 653-656, 1998
We have performed multicanonical Monte Carlo simulations of C-peptide of ribonuclease A. It is known by CD and NMR experiments that this peptide has high alpha-helix content in aqueous solution and that the side-chain charges of residues Glu-2$^-$ and His-12$^+$ play an important role in the stability of the alpha-helix.
arxiv  

Transcriptional control of an essential ribozyme in Drosophila reveals an ancient evolutionary divide in animals. [PDF]

open access: yesPLoS Genetics, 2015
Ribonuclease P (RNase P) is an essential enzyme required for 5'-maturation of tRNA. While an RNA-free, protein-based form of RNase P exists in eukaryotes, the ribonucleoprotein (RNP) form is found in all domains of life.
Sathiya N Manivannan   +3 more
doaj   +1 more source

Antibodies in human serum that precipitate ribonuclease P. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1988
Sera from certain patients with systemic lupus erythematosus (SLE) and related rheumatic diseases contain antibodies that selectively deplete extracts of HeLa cells of RNase P activity. Most of the sera that recognize RNase P, an endoribonuclease with an essential RNA subunit, also contain antibodies against another small ribonucleoprotein known as the
John A. Hardin   +4 more
openaire   +3 more sources

On nonhyperbolicity of P/P and P/SF knots in $S^3$ [PDF]

open access: yesarXiv, 2020
In [B90] or an available version [B18], Berge constructed twelve families of primitive/primitve(or simply P/P) knots, which are referred to as the Berge knots. It is proved in [B08] or independently in [G13] that all P/P knots are the Berge knots, which gives the complete classification of P/P knots.
arxiv  

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