Results 61 to 70 of about 108,983 (200)

Eukaryotic Ribonuclease P: A Plurality of Ribonucleoprotein Enzymes [PDF]

open access: yesAnnual Review of Biochemistry, 2002
▪ Abstract  Ribonuclease P (RNase P) is an essential endonuclease that acts early in the tRNA biogenesis pathway. This enzyme catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5′ end of tRNAs. RNase P activities have been identified in Bacteria, Archaea, and Eucarya, as well as organelles.
Shaohua, Xiao   +3 more
openaire   +2 more sources

A RNase P Ribozyme Inhibits Gene Expression and Replication of Hepatitis B Virus in Cultured Cells

open access: yesMicroorganisms, 2023
Hepatitis B virus (HBV), an international public health concern, is a leading viral cause of liver disease, such as hepatocellular carcinoma. Sequence-specific ribozymes derived from ribonuclease P (RNase P) catalytic RNA are being explored for gene ...
Bin Yan   +3 more
doaj   +1 more source

NASSAM: a server to search for and annotate tertiary interactions and motifs in three-dimensional structures of complex RNA molecules [PDF]

open access: yes, 2012
Similarities in the 3D patterns of RNA base interactions or arrangements can provide insights into their functions and roles in stabilization of the RNA 3D structure.
Ban   +21 more
core   +1 more source

Characterization of one new non-S-RNase of Armeniaca cathayana

open access: yesCzech Journal of Genetics and Plant Breeding, 2019
Armeniaca cathayana, a new species described in 2010, belongs to gametophytic self-incompatibility (GSI) system which is under S-allele control. One new non-S-ribonuclease (non-S-RNase) was found in A. cathayana through comparing its nucleotide and amino
Mengpei Liu   +4 more
doaj   +1 more source

Development of methods for capillary isoelectric focusing of dairy proteins : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]

open access: yes, 2006
Capillary Isoelectric Focusing (CIEF) is a high-resolution technique which can be applied to the separation and characterisation of complex biological mixtures such as dairy proteins.
Gapper, Leyton William
core  

Detection of MicroRNAs in Dried Serum Blots [PDF]

open access: yes, 2010
MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Reema Mallick   +2 more
core   +2 more sources

Ribonucleases P/MRP and the Expanding Ribonucleoprotein World [PDF]

open access: yesIUBMB Life, 2012
AbstractOne of the hallmarks of life is the widespread use of certain essential ribozymes. The ubiquitous ribonuclease P (RNase P) and eukaryotic RNase MRP are essential complexes where a structured, noncoding RNA acts in catalysis. Recent discoveries have elucidated the three‐dimensional structure of the ancestral ribonucleoprotein complex, suggested ...
Aaron, Hernandez-Cid   +3 more
openaire   +2 more sources

High sensitivity-low cost detection of SARS-CoV-2 by two steps end point RT-PCR with agarose gel electrophoresis visualization

open access: yesScientific Reports, 2021
More than one year since Coronavirus disease 2019 (COVID-19) pandemic outbreak, the gold standard technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection is still the RT-qPCR.
Solange Figueroa   +6 more
doaj   +1 more source

DNA-based S-genotyping of Japanese plum and pluot cultivars to clarify incompatibility relationships [PDF]

open access: yes, 2007
Diploid japanese plum (Prunus salicina Lindl.) cultivars are commonly self-incompatible. To date, 14 incompatibility alleles (S-alleles) have been identified and labeled with alphabetical (S-a-S-n) and 5 with numeric codes (S-1, S-3-S-6).
Halász, Júlia   +3 more
core   +1 more source

Crystal structure of a bacterial ribonuclease P RNA [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
The x-ray crystal structure of a 417-nt ribonuclease P RNA from Bacillus stearothermophilus was solved to 3.3-Å resolution. This RNA enzyme is constructed from a number of coaxially stacked helical domains joined together by local and long-range interactions.
Alexei V, Kazantsev   +5 more
openaire   +2 more sources

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