Results 11 to 20 of about 22,541 (295)
Microorganisms, 2022 The pandemic caused by SARS-CoV-2 is not over yet, despite all the efforts from the scientific community. Vaccination is a crucial weapon to fight this virus; however, we still urge the development of antivirals to reduce the severity and progression of ...
Margarida Saramago +9 more
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Preliminary studies on ribonucleases from Poa pratensis seeds
Acta Societatis Botanicorum Poloniae, 2015 Ribonuclease was extracted from Poa pratensis seeds with 0.1 M acetate buffer, pH 5.1, and then precipitated with alcohol. The enzyme was separated into 5 fractions (I-V) after chromatography on DEAE-cellulose at pH 5.1.
Irena Lorenc-Kubis +1 more
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Dual RNase and β-lactamase Activity of a Single Enzyme Encoded in Archaea
Life, 2020 β-lactam antibiotics have a well-known activity which disturbs the bacterial cell wall biosynthesis and may be cleaved by β-lactamases. However, these drugs are not active on archaea microorganisms, which are naturally resistant because of the lack of β ...
Seydina M. Diene +10 more
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Frontiers in Immunology, 2019 The development of novel treatment against tuberculosis is a priority global health challenge. Antimicrobial proteins and peptides offer a multifaceted mechanism suitable to fight bacterial resistance.
Lu Lu +6 more
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RNA-Binding Proteins Driving the Regulatory Activity of Small Non-coding RNAs in Bacteria
Frontiers in Molecular Biosciences, 2020 Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and activity of bacterial small RNAs.
Ana P. Quendera +6 more
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Acta Societatis Botanicorum Poloniae, 2014 Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska +1 more
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When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria
International Journal of Microbiology, 2012 It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host.
Brian C. Jester +2 more
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The Immunomodulatory and Antimicrobial Properties of the Vertebrate Ribonuclease A Superfamily
Vaccines, 2018 The Ribonuclease A Superfamily is composed of cationic peptides that are secreted by immune cells and epithelial tissues. Although their physiological roles are unclear, several members of the vertebrate Ribonuclease A Superfamily demonstrate ...
Laura Schwartz +3 more
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Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 The gene coding for the RNA subunit of ribonuclease P (RNase P) is essential in all free-living organisms. The RNA subunit, itself, is an enzyme and, from its evolutionary tree, we can infer that it is a very ancient molecule. The specificity of this enzyme is that it cleaves other RNA molecules at the junction of single-stranded and the 5′ end of ...
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Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins
Insects, 2013 The fungal pathogen Hirsutella thompsonii produces an insecticidal protein named hirsutellin A (HtA), which has been described to be toxic to several species of mites, insect larvae, and cells.
Álvaro Martínez del Pozo +6 more
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