Results 21 to 30 of about 22,100 (253)
Frontiers in Immunology, 2019 The development of novel treatment against tuberculosis is a priority global health challenge. Antimicrobial proteins and peptides offer a multifaceted mechanism suitable to fight bacterial resistance.
Lu Lu +6 more
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Acta Societatis Botanicorum Poloniae, 2014 Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska +1 more
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Streptomyces RNases – Function and impact on antibiotic synthesis
Frontiers in Microbiology, 2023 Streptomyces are soil dwelling bacteria that are notable for their ability to sporulate and to produce antibiotics and other secondary metabolites. Antibiotic biosynthesis is controlled by a variety of complex regulatory networks, involving activators ...
George H. Jones
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Bacterial stress granule protects mRNA through ribonucleases exclusion [PDF]
arXivMembraneless droplets formed through liquid-liquid phase separation (LLPS) play a crucial role in mRNA storage, enabling organisms to swiftly respond to environmental changes. However, the mechanisms underlying mRNA integration and protection within droplets remain unclear.
Pei L +9 more
europepmc +2 more sources
When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria
International Journal of Microbiology, 2012 It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host.
Brian C. Jester +2 more
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The Immunomodulatory and Antimicrobial Properties of the Vertebrate Ribonuclease A Superfamily
Vaccines, 2018 The Ribonuclease A Superfamily is composed of cationic peptides that are secreted by immune cells and epithelial tissues. Although their physiological roles are unclear, several members of the vertebrate Ribonuclease A Superfamily demonstrate ...
Laura Schwartz +3 more
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Frontiers in Pharmacology, 2019 Tumour progression is accompanied by rapid cell proliferation, loss of differentiation, the reprogramming of energy metabolism, loss of adhesion, escape of immune surveillance, induction of angiogenesis, and metastasis.
Nadezhda Mironova, Valentin Vlassov
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Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins
Insects, 2013 The fungal pathogen Hirsutella thompsonii produces an insecticidal protein named hirsutellin A (HtA), which has been described to be toxic to several species of mites, insect larvae, and cells.
Álvaro Martínez del Pozo +6 more
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The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation
FEBS Open Bio, 2023 Biofilms provide an ecological advantage against many environmental stressors, such as pH and temperature, making it the most common life‐cycle stage for many bacteria.
Manuel Condinho +5 more
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Bistability of an In Vitro Synthetic Autoregulatory Switch [PDF]
ACS Synthetic Biology 2012, 2011 The construction of synthetic biochemical circuits is an essential step for developing quantitative understanding of information processing in natural organisms. Here, we report construction and analysis of an in vitro circuit with positive autoregulation that consists of just four synthetic DNA strands and three enzymes, bacteriophage T7 RNA ...
arxiv +1 more source