Results 101 to 110 of about 333 (143)

Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies

, 2012
The theoretical framework in which this study is framed concerns the internationalization of production dynamics of firms abroad. The international literature in this field argues that there is not a conventional definition nor a universally tested ...
Balestra, Dario
core  

Maize U2 snRNAs:Gene sequence and expression

, 1989
The complexity of plant U-type small nuclear ribonucleoprotein particles (UsnRNPs) may represent one level at which differences in splicing between animals and plants and between monocotyledonous and dicotyledonous plants could be effected.
Brown, John W. S., Waugh, Robbie; id_orcid   +1 more
core   +1 more source

Transcriptionally correlated subcellular dynamics of MBNL1 during lens development and their implication for the molecular pathology of myotonic dystrophy type 1

, 2014
This work is supported by the Scottish Universities Life Science Alliance (SULSA) and the Biotechnology and Biological Sciences Research Council (BBSRC) via a Ph.D.
Coleman, Stewart, Sleeman, Judith E., Coleman, Stewart M., Prescott, Alan R., Sleeman, Judith Elizabeth, Prescott, Alan R.; id_orcid   +5 more
core   +1 more source

An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly

, 1988
Splicing of nuclear precursor messenger RNA (pre-mRNA) occurs on a large ribonucleoprotein complex, the spliceosome. Several small nuclear ribonucleoproteins (snRNP's) are subunits of this complex that assembles on the pre-mRNA.
Abelson, John, Ruby, Stephanie W.
core  

SF3B2, a novel candidate gene for autosomal dominant retinitis pigmentosa, encodes a component of the U2 small nuclear ribonucleoprotein

, 2015
Purpose: Identification and functional characterisation of a novel candidate gene for autosomal dominant retinitis pigmentosa (adRP). Methods: Five affected and five unaffected individuals of a Belgian adRP family in which known adRP loci were excluded,
Van Cauwenbergh, Caroline, Hamel, Christian, De Baere, Elfride, Coppieters, Frauke, Vleminckx, Kris, Karlstetter, Marcus, Langmann, Thomas, Leroy, Bart, Manes, Gael, Hamel, Christian P   +9 more
core  

Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation

, 2001
The active 17S U2 small nuclear ribonucleoprotein particle (snRNP), which binds to the intron branch site during the formation of the prespliceosome, is assembled in vitro by sequential interactions of the essential splicing factors SF3b and SF3a with ...
Nesic, Dobrila, Kraemer, Angela
core   +1 more source

Spliceosomal Prp24 Unwinds A Minimal U2/u6 Complex From Yeast

, 2013
Splicing plays a major role in eukaryotic gene expression by processing pre-mRNA to form mature mRNA. Pre-mRNAs undergo splicing to remove introns, non–protein coding regions, and religate exons, protein coding regions.
Warnasooriya, Chandani Manoja
core  

The role of chromosome territories in the funtional compartmentalization of the cell nucleus [PDF]

, 1993
Scherthan, Harry, Dietzel, S., Mathieu, U. R., Ried, Thomas, Cremer, Christoph, Zirbel, R. M., Cremer, Thomas, Speicher, Michael R., Emmerich, Patricia, Kurz, A., Lichter, Peter, Jauch, Anna, Schröck, Evelin, Rinke, B.   +13 more
core   +1 more source

CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif

, 1998
A screen for suppressors of a U2 snRNA mutation identified CUS2, an atypical member of the RNA recognition motif (RRM) family of RNA binding proteins. CUS2 protein is associated with U2 RNA in splicing extracts and interacts with PRP11, a subunit of the ...
Kenneth J. Howe, Megan Neville, Rhonda Perriman, Haller Igel, Dong Yan   +4 more
core  

Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs.

Journal of Biological Chemistry, 1983
M, Hinterberger, I, Pettersson, J A, Steitz   +2 more
openaire   +2 more sources