Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice. [PDF]
Nature Communications, 2020 Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of functionally versatile proteins that play critical roles in the biogenesis, cellular localization and transport of RNA.
Feng, An-Chieh +14 more
core +2 more sources
Activation of Peptidylarginine Deiminase in the Salivary Glands of Balb/c Mice Drives the Citrullination of Ro and La Ribonucleoproteins [PDF]
Journal of Immunology Research, 2017 The goal of the present study was to determine whether peptidylarginine deiminase PAD2 and PAD4 enzymes are present in Balb/c mouse salivary glands and whether they are able to citrullinate Ro and La ribonucleoproteins.
Avalos Díaz, Esperanza del Refugio +7 more
core +3 more sources
The TROVE module: A common element in Telomerase, Ro and Vault ribonucleoproteins [PDF]
BMC Bioinformatics, 2003 BACKGROUND: Ribonucleoproteins carry out a variety of important tasks in the cell. In this study we show that a number of these contain a novel module, that we speculate mediates RNA-binding.
Bateman, Alex, Kickhoefer, Valerie
core +5 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the causative agent of Chagas Disease, lives intracellularly within host cells.
Camila Gachet-Castro +6 more
doaj +1 more source
Compendium of Methods to Uncover RNA-Protein Interactions In Vivo
Methods and Protocols, 2021 Control of gene expression is critical in shaping the pro-and eukaryotic organisms’ genotype and phenotype. The gene expression regulatory pathways solely rely on protein–protein and protein–nucleic acid interactions, which determine the fate of the ...
Mrinmoyee Majumder +1 more
doaj +1 more source
Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus
eLife, 2023 Rotaviruses transcribe 11 distinct RNAs that must be co-packaged prior to their replication to make an infectious virion. During infection, nontranslating rotavirus transcripts accumulate in cytoplasmic protein-RNA granules known as viroplasms that ...
Sebastian Strauss +6 more
doaj +1 more source
Noncanonical Functions and Cellular Dynamics of the Mammalian Signal Recognition Particle Components
Frontiers in Molecular Biosciences, 2021 The signal recognition particle (SRP) is a ribonucleoprotein complex fundamental for co-translational delivery of proteins to their proper membrane localization and secretory pathways.
Camilla Faoro, Sandro F. Ataide
doaj +1 more source
SMN post-translational modifications in spinal muscular atrophy
Frontiers in Cellular Neuroscience, 2023 Since its first identification as the gene responsible for spinal muscular atrophy (SMA), the range of survival motor neuron (SMN) protein functions has increasingly expanded.
Giulietta M. Riboldi +3 more
doaj +1 more source
The Role of RNA Binding Proteins for Local mRNA Translation: Implications in Neurological Disorders
Frontiers in Molecular Biosciences, 2020 As neurons are one of the most highly polarized cells in our body, they require sophisticated cellular mechanisms to maintain protein homeostasis in their subcellular compartments such as axons and dendrites.
Maximilian Paul Thelen, Min Jeong Kye
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2020 Objective To observe the efficiency of Cas9 RNP technology for the preparation of B2M and PD-1 double genes knock-out primary human T lymphocytes (hereinafter referred to as T cells).
XU Ya +3 more
doaj +1 more source