Results 21 to 30 of about 25,962 (290)
The Role of RNA Binding Proteins for Local mRNA Translation: Implications in Neurological Disorders
Frontiers in Molecular Biosciences, 2020 As neurons are one of the most highly polarized cells in our body, they require sophisticated cellular mechanisms to maintain protein homeostasis in their subcellular compartments such as axons and dendrites.
Maximilian Paul Thelen, Min Jeong Kye
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The Ribonucleoprotein Csr Network [PDF]
International Journal of Molecular Sciences, 2013 Ribonucleoprotein complexes are essential regulatory components in bacteria. In this review, we focus on the carbon storage regulator (Csr) network, which is well conserved in the bacterial world. This regulatory network is composed of the CsrA master regulator, its targets and regulators.
Seyll, Ethel, Van Melderen, Laurence
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, 2021 Induced pluripotent stem cells (iPSCs) have become widely used for disease modelling, particularly with regard to predisposing genetic risk factors and causal gene variants.
Nguyen Tran, Minh Thuan +8 more
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Ribonucleoprotein multimers and their functions [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2010 Ribonucleoproteins (RNPs) play key roles in many cellular processes and often function as RNP enzymes. Similar to proteins, some of these RNPs exist and function as multimers, either homomeric or heteromeric. While in some cases the mechanistic function of multimerization is well understood, the functional consequences of multimerization of other RNPs ...
Franziska, Bleichert, Susan J, Baserga
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Biogenesis of telomerase ribonucleoproteins [PDF]
RNA, 2012 Telomerase adds simple-sequence repeats to the ends of linear chromosomes to counteract the loss of end sequence inherent in conventional DNA replication. Catalytic activity for repeat synthesis results from the cooperation of the telomerase reverse transcriptase protein (TERT) and the template-containing telomerase RNA (TER).
Emily D, Egan, Kathleen, Collins
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Ribonucleoprotein bodies are phased in [PDF]
Biochemical Society Transactions, 2016 Intracellular compartments are necessary for the regulation of many biochemical processes that ensure cell survival, growth and proliferation. Compartmentalisation is commonly achieved in organelles with defined lipid membranes, such as mitochondria, endoplasmic reticulum or the Golgi apparatus. While these organelles are responsible for many localised
Sfakianos, Aristeidis +2 more
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Ribonucleoprotein complexes as autoantigens [PDF]
Current Opinion in Immunology, 1995 Many intracellular proteins and nucleic acids, that are involved in important biosynthetic pathways, are targeted by autoantibodies occurring spontaneously in the sera of patients with systemic autoimmune diseases. Frequently, the autoantigens are assembled into multicomponent complexes containing both nucleic acid(s) and proteins.
Venrooij, W.J. van, Pruijn, G.J.M.
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Sequence alignment, aaTR composition, and predicted structures of Borg Sm ribonucleoproteins.
, 2023 (A) Multiple sequence alignment of Borg Sm ribonucleoproteins with and without aaTRs, Sm from Methanoperedens bins co-occurring with Borgs, and reference sequences from M. jannaschii (PDB: 4X9D), M. nitroreducens (WP_096203417), and E. coli (PDB: 1HK9). (
Rohan Sachdeva (2926581) +4 more
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Zhongliu Fangzhi Yanjiu, 2020 Objective To observe the efficiency of Cas9 RNP technology for the preparation of B2M and PD-1 double genes knock-out primary human T lymphocytes (hereinafter referred to as T cells).
XU Ya +3 more
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Structure of spliceosomal ribonucleoproteins [PDF]
F1000 Biology Reports, 2010 Splicing of the precursors of eukaryotic mRNA and some non-coding RNAs is catalyzed by the 'spliceosome', which comprises five RNA-protein complexes (small nuclear ribonucleoproteins, or snRNPs) that assemble in an ordered manner onto precursor-mRNAs. Much progress has been made in determining the gross morphology of spliceosomal assembly intermediates.
Krummel, Daniel Aaron Pomeranz +2 more
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