Results 181 to 190 of about 24,694 (278)

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

The enigma of nuclear FMRP: facts and myths. [PDF]

Front Cell Dev Biol
Khandjian EW, Davidovic L.
europepmc   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source

Regulation of long non-coding RNAs by essential oils: Therapeutic implications in human diseases. [PDF]

Genet Mol Biol
Agostini LDC, Teixeira MSDS, Silva GND.
europepmc   +1 more source

NPF2 is involved in intracellular pH regulation and ion balance in the diatom Phaeodactylum tricornutum

New Phytologist, Volume 250, Issue 6, Page 3885-3899, June 2026.
Summary Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests.
Anna Santin, Monia Teresa Russo, Dany Croteau, Antonella Ruggiero, Sara Russo Spena, Laura Morales de los Rios, Claire Corratge‐Faillie, Seleem Brignone, Benoit Lacombe, Remo Sanges, Maurizio Chiurazzi, Maurizio Ribera d'Alcalà, Benjamin Bailleul, Angela Falciatore, Maria Immacolata Ferrante, Alessandra Rogato   +15 more
wiley   +1 more source

Breaking barriers: Respiratory viral strategies targeting the host's nuclear pore complex and nuclear transport pathways. [PDF]

Mol Biol Cell
Udi Y, Aitchison JD, Rout MP, Obado S.
europepmc   +1 more source

Enhancing CRISPR/Cas‐Mediated Gene Knockout With Short Non‐Homologous Oligonucleotides

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3742-3753, June 2026.
ABSTRACT Chlamydomonas reinhardtii is a model green microalga that has great industrial potential as a sustainable bio‐factory for recombinant protein and high‐value chemical production. Efficient genome editing tools are required to redesign this organism for synthetic biology applications. CRISPR‐Cas editing technologies have already been adapted for
Yen Peng Chew, Aron Ferenczi, Marie Dannay, Cristina Ponce‐Lilly, Adam Kovac, Dávid Tóth, Szilvia Z. Tóth, Attila Molnar   +7 more
wiley   +1 more source

The role of circRNAs in N⁶-methyladenosine(m⁶A), cell death and clinical applications in human breast cancer. [PDF]

Sci Prog
Chen S, Mao J, Zhuang X, Jiang Y, Zou Y, Xiang M, Shu Y.   +6 more
europepmc   +1 more source

Targeting DNMT1 Attenuates Radiation‐Induced Heart Disease: An Integrated Multiomic and Functional Study

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Our study elucidates that DNMT1 promotes radiation‐induced heart disease by orchestrating aberrant epigenetic regulation and impairing cardioprotective signaling. Inhibition of DNMT1 mitigates this damage, revealing a translatable strategy to prevent RIHD.
Gang Wang, Yan‐ling Li, Bo‐wen Wang, Rong Wang, Yan Wang, Yan‐biao Shu, Wen‐bo Zhang, Pan Wu, Yu‐jie Hu, Wei‐jie Lu, Ping Xie   +10 more
wiley   +1 more source

Cajal's organization of neuronal nucleus revisited. [PDF]

Front Neuroanat
Lafarga M, Berciano MT, Narcís JO, Baltanás FC, Tapia O.   +4 more
europepmc   +1 more source