Results 1 to 10 of about 903,676 (211)
U2.3 Precursor Small Nuclear RNA in vitro Processing Assay
Bio-Protocol, 2021 Small nuclear RNAs (snRNAs) are vital for eukaryotic cell activities and play important roles in pre-mRNA splicing. The molecular mechanism underlying the transcription of snRNA, regulated via upstream/downstream cis-elements and relevant trans-elements,
Chan Lin +5 more
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Cell Reports, 2023 Summary: Argonaute/small RNA pathways and heterochromatin work together to propagate transgenerational gene silencing, but the mechanisms behind their interaction are not well understood.
Yue-He Ding +4 more
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Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis
Frontiers in Molecular Biosciences, 2023 Introduction: The anterior cruciate ligament (ACL) is susceptible to degeneration, resulting in joint pain, reduced mobility, and osteoarthritis development.
Yalda A. Kharaz +6 more
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Identification of small RNA in polyhedra of Bombyx mori nuclear polyhedrosis virus [PDF]
The Ukrainian Biochemical Journal, 2014 It has been shown by bioinformatic methods that regions of the Bombyx mori viral nuclear polyhedrosis genome encoded two small RNA – snc RNA-1 and snc RNA-2, which could perform a structural function in polyhedra crystals formation.
T. V. Shirina +3 more
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Non-Coding RNA, 2023 Traditionally, small molecule-based drug discovery has mainly focused on proteins as the drug target. Opening RNA as an additional target space for small molecules offers the possibility to therapeutically modulate disease-driving non-coding RNA targets ...
Nina Zablowsky +8 more
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Architecture of the U5 small nuclear RNA. [PDF]
Molecular and Cellular Biology, 1994 We have used comparative sequence analysis and deletion analysis to examine the secondary structure of the U5 small nuclear RNA (snRNA), an essential component of the pre-mRNA splicing apparatus. The secondary structure of Saccharomyces cerevisiae U5 snRNA was studied in detail, while sequences from six other fungal species were included in the ...
D N, Frank, H, Roiha, C, Guthrie
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The epitranscriptome of small non-coding RNAs
Non-coding RNA Research, 2021 Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.
Xiaoyu Li, Jinying Peng, Chengqi Yi
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Journal of Ovarian Research, 2021 Nuclear small RNAs have emerged as an important subset of non-coding RNA species that are capable of regulating gene expression. A type of small RNA, microRNA (miRNA) have been shown to regulate development of the ovarian follicle via canonical targeting
Derek Toms +3 more
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PARN and TOE1 Constitute a 3′ End Maturation Module for Nuclear Non-coding RNAs
Cell Reports, 2018 Summary: Poly(A)-specific ribonuclease (PARN) and target of EGR1 protein 1 (TOE1) are nuclear granule-associated deadenylases, whose mutations are linked to multiple human diseases.
Ahyeon Son, Jong-Eun Park, V. Narry Kim
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Structure of a rare non-standard sequence k-turn bound by L7Ae protein [PDF]
, 2014 Kt-23 from Thelohania solenopsae is a rare RNA kink turn (k-turn) where an adenine replaces the normal guanine at the 2n position. L7Ae is a member of a strongly conserved family of proteins that bind a range of k-turn structures in the ribosome, box C/D
Huang, Lin, Lilley, David M J
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