Results 21 to 30 of about 573,592 (269)

New small nuclear RNA gene-like transcriptional units as sources of regulatory transcripts. [PDF]

PLoS Genetics, 2007
By means of a computer search for upstream promoter elements (distal sequence element and proximal sequence element) typical of small nuclear RNA genes, we have identified in the human genome a number of previously unrecognized, putative transcription ...
Aldo Pagano, Manuele Castelnuovo, Federico Tortelli, Roberto Ferrari, Giorgio Dieci, Ranieri Cancedda   +5 more
doaj   +1 more source

Species Diversity, Molecular Phylogeny, and Ecological Habits of Fomitopsis (Polyporales, Basidiomycota)

Frontiers in Microbiology, 2022
Fomitopsis is a worldwide brown-rot fungal genus of Polyporales, which grows on different gymnosperm and angiosperm trees and has important ecological functions and economic values.
Shun Liu, Chang-Ge Song, Tai-Min Xu, Xing Ji, Dong-Mei Wu, Bao-Kai Cui   +5 more
doaj   +1 more source

Ancient Origin of the U2 Small Nuclear RNA Gene-Targeting Non-LTR Retrotransposons Utopia. [PDF]

PLoS ONE, 2015
Most non-long terminal repeat (non-LTR) retrotransposons encoding a restriction-like endonuclease show target-specific integration into repetitive sequences such as ribosomal RNA genes and microsatellites.
Kenji K Kojima, Jerzy Jurka
doaj   +1 more source

Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate

Cell Reports, 2017
The nuclear cap-binding complex (CBC) stimulates processing reactions of capped RNAs, including their splicing, 3′-end formation, degradation, and transport.
Simone Giacometti, Nour El Houda Benbahouche, Michal Domanski, Marie-Cécile Robert, Nicola Meola, Michal Lubas, Jakob Bukenborg, Jens S. Andersen, Wiebke M. Schulze, Celine Verheggen, Grzegorz Kudla, Torben Heick Jensen, Edouard Bertrand   +12 more
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

The disease resistance protein SNC1 represses the biogenesis of microRNAs and phased siRNAs

Nature Communications, 2018
A small RNA-based signaling cascade prevents the induction of plant resistance genes (R-genes) in the absence of pathogen challenge. Here Cai et al.
Qiang Cai, Chao Liang, Suikang Wang, Yingnan Hou, Lei Gao, Li Liu, Wenrong He, Wenbo Ma, Beixin Mo, Xuemei Chen   +9 more
doaj   +1 more source

Precursors of U4 small nuclear RNA. [PDF]

The Journal of cell biology, 1984
The processing and ribonucleoprotein assembly of U4 small nuclear RNA has been investigated in HeLa cells. After a 45-min pulse label with [3H]uridine, a set of apparently cytoplasmic RNAs was observed migrating just behind the gel electrophoretic position of mature U4 RNA.
S J, Madore, E D, Wieben, G R, Kunkel, T, Pederson   +3 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Sphingomyelin regulates the transcriptional machinery in nuclear lipid microdomains

Communications Biology
Nuclear lipid microdomains rich in sphingomyelin and cholesterol content regulate double-stranded exonuclease-resistant RNA. The study aimed to elucidate the importance of nuclear lipid microdomains in safeguarding nuclear RNA from digestion and to ...
Carmela Conte, Michela Bulfoni, Federico Fiorani, Samuela Cataldi, Nicolò Gualandi, Ornella Calderini, Mercedes Garcia-Gil, Giorgia Vesca, Rita Paroni, Michele Dei Cas, Cataldo Arcuri, Alessandra Mirarchi, Tommaso Beccari, Toshihide Kobayashi, Nario Tomishige, Paola Signorelli, Francesco Curcio, Elisabetta Albi   +17 more
doaj   +1 more source

Small nuclear RNAs in the ciliateTetrahymena

Nucleic Acids Research, 1985
We have isolated and partially characterized a family of small nuclear RNAs (snRNAs) from three different species of the protozoan Tetrahymena. We find six distinct snRNAs ranging in size from 100 to 250 nucleotides. The two largest snRNAs, as well as an abundant, heterogenous group of smaller snRNAs are found in the nucleolar RNA fraction. None of the
N, Pedersen, P, Hellung-Larsen, J, Engberg   +2 more
openaire   +3 more sources