Results 161 to 170 of about 38,830 (350)

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

open access: yesVIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou   +6 more
wiley   +1 more source

Incorporation of Amino Acids into Protein in a System Containing Rat Liver Ribonucleoprotein Particles and Chick Liver Cell Sap. [PDF]

open access: bronze, 1963
Alexandra von der Decken   +4 more
openalex   +1 more source

Strand displacement‐driven CRISPR/Cas12a framework enables precise identification of low‐abundance point mutations

open access: yesVIEW, EarlyView.
We established an engineered CRISPR/Cas12a point mutation detection strategy (E‐CRISPR) for low‐abundance point mutations detection. By integrating the precise regulatory mechanism of strand displacement reaction (SDR) with the local high‐concentration probe microenvironment created by tetrahedral DNA frameworks (TDFs), it has achieved simultaneous ...
Jiaxi Mo   +11 more
wiley   +1 more source

Characterization of the Messenger Ribonucleoprotein Released from Reticulocyte Polyribosomes by EDTA Treatment [PDF]

open access: bronze, 1971
Bernard Lebleu   +5 more
openalex   +1 more source

Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle

open access: yesFASEB BioAdvances, EarlyView.
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn   +5 more
wiley   +1 more source

The Duck‐Globin Messenger‐Ribonucleoprotein Complex [PDF]

open access: bronze, 1973
Carlos Morel   +4 more
openalex   +1 more source

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells

open access: yesCell Reports, 2016
Summary: New genetic tools are needed to understand the functional interactions between HIV and human host factors in primary cells. We recently developed a method to edit the genome of primary CD4+ T cells by electroporation of CRISPR/Cas9 ...
Judd F. Hultquist   +8 more
doaj  

Role of mitochondrial complex I genes in host plant expansion of Bactrocera tau (Tephritidae: Diptera) by CRISPR/Cas9 system

open access: yesInsect Science, EarlyView.
The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi   +3 more
wiley   +1 more source

Ribonucleoprotein Particles in HeLa Cells [PDF]

open access: bronze, 1972
Gerd Wengler   +2 more
openalex   +1 more source

Home - About - Disclaimer - Privacy