Results 241 to 250 of about 26,288 (294)

Cardioprotective potential of shikonin in cardiac hypertrophy is mediated through PKM2/c-Myc/PTBP1/HIF-1α signaling pathway.

Indian J Pharmacol
Rihan M, Sharma SS.
europepmc   +1 more source

Glycoalkaloid‐Free Starch Potatoes Generated by CRISPR/Cas9‐Mediated Mutations of Genes in the Glycoalkaloid Biosynthesis Pathway Enable More Sustainable Uses of By‐Products From Starch Production

Plant Biotechnology Journal, EarlyView.
ABSTRACT Steroidal glycoalkaloids (SGAs) are toxic cholesterol‐derived secondary metabolites present in several Solanaceae species. In potato, tuber SGA levels are for reasons of toxicity of concern in both table and starch cultivars. In the latter, SGAs bind to proteins and fibres in starch production side‐streams and prevent their further uses as ...
Ying Liu, Irene Merino, Mareike Gutensohn, Annika I. Johansson, Kalle Johansson, Mariette Andersson, Per Hofvander, Folke Sitbon   +7 more
wiley   +1 more source

RNA aptamers as tools for the purification and analysis of in vivo assembled ribonucleoproteins. [PDF]

RNA
Rocca DG, Kothe U.
europepmc   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

Structural and biochemical studies of mobile retrotransposon proteins in action. [PDF]

Curr Opin Struct Biol
Thawani A, Collins K, Nogales E.
europepmc   +1 more source

Protoplast‐Based Functional Genomics and Genome Editing: Progress, Challenges and Applications

Plant, Cell &Environment, EarlyView.
ABSTRACT Protoplast‐based systems provide a powerful and versatile platform for exploring how plants sense and respond to their environment. By enabling the direct delivery of proteins, DNA, and RNA into plant cells after cell wall removal, this approach facilitates precise molecular dissection of signaling, stress adaptation, and gene regulation ...
Jo‐Wei Allison Hsieh, Fu‐Hui Wu, Dian‐Xuan Yang, Ai‐En Wu, Ching‐Ann Liu, Chang‐Hung Chen, Shinn‐Zong Lin, Ying‐Chung Jimmy Lin, Choun‐Sea Lin   +8 more
wiley   +1 more source

Cajal's organization of neuronal nucleus revisited. [PDF]

Front Neuroanat
Lafarga M, Berciano MT, Narcís JO, Baltanás FC, Tapia O.   +4 more
europepmc   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Muscle-specific gene editing therapy via mammalian fusogen-directed virus-like particles. [PDF]

Nat Commun
Zhou SK, Luo JT, Chen YF, Lu ZD, Jian QH, Jiang SQ, Li J, Zhang XQ, Tan XY, Yang XZ, Xu CF, Wang J.   +11 more
europepmc   +1 more source