Results 241 to 250 of about 38,830 (350)

Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing. [PDF]

open access: yesNucleic Acids Res
Karp H   +7 more
europepmc   +1 more source

Recent advances in proteomic workflows to interrogate the SUMOylome in plants

open access: yesNew Phytologist, Volume 247, Issue 1, Page 90-96, July 2025.
Summary Protein posttranslational modifications (PTMs) are vital for regulating protein functions. SUMOylation, a PTM essential for plant survival, involves attaching a Small Ubiquitin‐like MOdifier (SUMO) to lysine residues of target proteins. SUMOylation influences stress tolerance, cell proliferation, protein stability, and gene expression.
Kishor D. Ingole   +3 more
wiley   +1 more source

Author Correction: Engineering self-deliverable ribonucleoproteins for genome editing in the brain. [PDF]

open access: yesNat Commun
Chen K   +6 more
europepmc   +1 more source

Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 25, June 17, 2025.
Spiders exhibit unique traits with significant implications for a diversity of fields, and gene editing provides new opportunities for advancing research in these areas. In this study, we developed a CRISPR‐Cas9 protocol for spiders, enabling gene knock‐outs/knock‐ins to study gene function and introduce new phenotypic traits. Abstract CRISPR‐Cas9 gene
Edgardo Santiago‐Rivera   +1 more
wiley   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, Volume 19, Issue 6, Page 1876-1893, June 2025.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

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