Results 21 to 30 of about 57,913 (382)
Xist ribonucleoproteins promote female sex-biased autoimmunity
Cell, 2023 Autoimmune diseases disproportionately affect females more than males. The XX sex chromosome complement is strongly associated with susceptibility to autoimmunity.
Diana R. Dou +23 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 The heterogeneous nuclear ribonucleoproteins (hnRNPs) are a diverse family of RNA binding proteins that are implicated in RNA metabolism, such as alternative splicing, mRNA stabilization and translational regulation. According to their different cellular
Jingming Wang +16 more
semanticscholar +1 more source
High-purity production and precise editing of DNA base editing ribonucleoproteins
Science Advances, 2021 Cytosine and adenine base editor ribonucleoproteins show precise base editing with reduced DNA and RNA off-target effects.
Hyeon-Ki Jang +9 more
semanticscholar +1 more source
The Ribonucleoprotein Csr Network [PDF]
International Journal of Molecular Sciences, 2013 Ribonucleoprotein complexes are essential regulatory components in bacteria. In this review, we focus on the carbon storage regulator (Csr) network, which is well conserved in the bacterial world. This regulatory network is composed of the CsrA master regulator, its targets and regulators.
Seyll, Ethel, Van Melderen, Laurence
openaire +4 more sources
Ribonucleoprotein bodies are phased in [PDF]
Biochemical Society Transactions, 2016 Intracellular compartments are necessary for the regulation of many biochemical processes that ensure cell survival, growth and proliferation. Compartmentalisation is commonly achieved in organelles with defined lipid membranes, such as mitochondria, endoplasmic reticulum or the Golgi apparatus. While these organelles are responsible for many localised
Sfakianos, Aristeidis +2 more
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Ribonucleoprotein Immunoprecipitation (RIP) Analysis [PDF]
BIO-PROTOCOL, 2020 RNAs and RNA-binding proteins (RBPs) can interact dynamically in ribonucleoprotein (RNP) complexes that play important roles in controlling gene expression programs. One of the powerful ways to investigate changes in the association of RNAs with an RBP of interest is by immunoprecipitation (IP) analysis of native RNPs.
Martindale, Jennifer +2 more
openaire +4 more sources
H/ACA Small Ribonucleoproteins: Structural and Functional Comparison Between Archaea and Eukaryotes
Frontiers in Microbiology, 2021 During ribosome synthesis, ribosomal RNA is modified through the formation of many pseudouridines and methylations which contribute to ribosome function across all domains of life.
D. P. Czekay, Ute Kothe
semanticscholar +1 more source
Ribonucleoprotein complexes as autoantigens [PDF]
Current Opinion in Immunology, 1995 Many intracellular proteins and nucleic acids, that are involved in important biosynthetic pathways, are targeted by autoantibodies occurring spontaneously in the sera of patients with systemic autoimmune diseases. Frequently, the autoantigens are assembled into multicomponent complexes containing both nucleic acid(s) and proteins.
Venrooij, W.J. van, Pruijn, G.J.M.
openaire +4 more sources
Structure of spliceosomal ribonucleoproteins [PDF]
F1000 Biology Reports, 2010 Splicing of the precursors of eukaryotic mRNA and some non-coding RNAs is catalyzed by the 'spliceosome', which comprises five RNA-protein complexes (small nuclear ribonucleoproteins, or snRNPs) that assemble in an ordered manner onto precursor-mRNAs. Much progress has been made in determining the gross morphology of spliceosomal assembly intermediates.
Kiyoshi Nagai +2 more
openaire +3 more sources
Ribonucleoprotein multimers and their functions [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2010 Ribonucleoproteins (RNPs) play key roles in many cellular processes and often function as RNP enzymes. Similar to proteins, some of these RNPs exist and function as multimers, either homomeric or heteromeric. While in some cases the mechanistic function of multimerization is well understood, the functional consequences of multimerization of other RNPs ...
Franziska Bleichert, Susan J. Baserga
openaire +2 more sources