Results 281 to 290 of about 32,025 (309)

Degradation of pyrimidine ribonucleosides by Pseudomonas aeruginosa

Antonie van Leeuwenhoek, 1996
Pyrimidine ribonucleoside degradation in the human pathogen Pseudomonas aeruginosa ATCC 15692 was investigated. Either uracil, cytosine, 5-methylcytosine, thymine, uridine or cytidine supported P. aeruginosa growth as a nitrogen source when glucose served as the carbon source.
openaire   +3 more sources

Selective deacylation of peracylated ribonucleosides

Tetrahedron Letters, 2009
Abstract A protocol for chemoselective deprotection of N,O-acylated ribonucleosides has been developed. Peracylated pyrimidine ribonucleosides subjected to guanidinium nitrate and NaOMe in MeOH/CH 2 Cl 2 at 0 °C undergo high yielding O-deacylation, while even more pronounced chemoselectivity is observed with peracylated purine ribonucleosides as O5′-
Patrick J. Hrdlicka, Dale C. Guenther, Jared W. Rigoli, Michael E. Østergaard, Kirsten M. Canady   +4 more
openaire   +2 more sources

Continuous monitoring of Pi release following nucleotide hydrolysis in actin or tubulin assembly using 2-amino-6-mercapto-7-methylpurine ribonucleoside and purine-nucleoside phosphorylase as an enzyme-linked assay.

Biochemistry, 1996
ATP and GTP are hydrolyzed during self-assembly of actin and tubulin, respectively. It is known that nucleotide is hydrolyzed on the polymer in two consecutive steps, chemical cleavage of the gamma-phosphate followed by the slower release of Pi.
Ronald Melki, S. Fievez, M. Carlier
semanticscholar   +1 more source

Synthesis of acylphosphates of purine ribonucleosides

Tetrahedron Letters, 1996
Abstract Nucleotides do not penetrate cells at a sufficient rate to realize their therapeutic potential. To overcome this limitation we have envisaged acyl nucleodi(tri)phosphates (ND(T)Ps) as suitable membrane permeable prodrugs because a) preliminary experiences have shown that these compounds are preferably cleaved at their mixed carboxylic ...
Annett Kreimeyer, Joël Ughetto-Monfrin, Abdelkader Namane, Tam Huynh-Dinh   +3 more
openaire   +2 more sources

Some Aspects of Ribonucleoside Chemistry

Nucleosides and Nucleotides, 1985
Abstract New routes to the preparations of 2′-deoxy-3′-C-methyl uridine (2c) and 1-(5′-0-trityl-3′-deoxy-β-D-glycero-pentofuran-2-ulosyl)uracil (4) from 5′-0-trityl-2′-0-tosyl uridine (1) and 5′-0-trityl-3′-0-tosyl uridine (3) respectively are described.
Jyoti Chattopadhyaya, S. Juntunen, H. Essadiq, Annie Grouiller   +3 more
openaire   +2 more sources

2-Fluoropurine ribonucleosides

Journal of Medicinal Chemistry, 1970
Kathleen Hewson, John A. Montgomery
openaire   +3 more sources

Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets

Nature Microbiology, 2021
Richard K Plemper, Robert M Cox
exaly  

Simplified diethylaminoethylcellulose chromatography of ribonucleosides

Analytical Biochemistry, 1971
Barbara H. Smith, Joseph MacGee
openaire   +3 more sources

Effect of Deer Antler Extract on Muscle Differentiation and 5-Aminoimidazole-4-Carboxamide Ribonucleoside (AICAR)-Induced Muscle Atrophy in C2C12 Cells

Food Science of Animal Resources, 2021
Woo Young Jang, Beom Sik Yun, Jin Soo Kim   +2 more
exaly  

Acyl migration in ribonucleoside derivatives

Tetrahedron Letters, 1965
Colin B. Reese, D.R. Trentham
openaire   +3 more sources