Results 81 to 90 of about 7,940 (153)

A General Method for Selective Tritylation of Primary Hydroxyl Groups in Carbohydrates and Related Compounds [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1989
A general and rapid procedure is developed for the selective tritylation of the 'primary OH-function of the four common ribonucleosides, ascorbic acid, and polyhydric compounds.
doaj  

Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications

open access: yesCurrent Protocols, Volume 6, Issue 2, February 2026.
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley   +1 more source

Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles [PDF]

open access: yes, 2014
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Langmuir, copyright © American Chemical Society after peer review and technical editing by publisher.
Kelly, Erin Y.   +5 more
core   +1 more source

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho   +13 more
wiley   +1 more source

Synthesis and antiviral activity of novel spirocyclic nucleosides [PDF]

open access: yes, 2018
The synthesis of a number of spirocyclic ribonucleosides containing either a triazolic or azetidinic system is described, along with two analogous phosphonate derivatives of the former.
Abdulsattar, Ban O.   +9 more
core   +1 more source

Sex‐Specific Renal Proteomic Responses to Mycotoxins and Their Mitigation by Bioactive Food Ingredients

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 4, 26 February 2026.
In vivo exposure to AFB1 and OTA markedly disrupts proteomic patterns in rats, with males showing heightened sensitivity. Fermented whey and pumpkin alleviated toxin‐induced molecular damage by decreasing differentially expressed proteins, demonstrating their potential to mitigate molecular disturbances and supporting their role as functional dietary ...
Fojan Agahi   +2 more
wiley   +1 more source

Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance

open access: yesFrontiers in Molecular Biosciences, 2017
Nucleoside reverse transcriptase inhibitors (NRTIs) were the first drugs used to treat human immunodeficiency virus (HIV) the cause of acquired immunodeficiency syndrome.
Matthew J. Young
doaj   +1 more source

Salvage enzymes in nucleotide biosynthesis [PDF]

open access: yes, 2007
Balanced pools of deoxyribonucleoside triphosphates (dNTPs), the building blocks of DNA, and ribonucleoside triphosphates (NTPs), the precursors of RNA, are crucial for a controlled cell proliferation.
Kosinska, Urszula
core  

A ‘bottom up’, ab initio computational approach to understanding fundamental photophysical processes in nitrogen containing heterocycles, DNA bases and base pairs [PDF]

open access: yes, 2016
A systematic computational study of non-radiative decay pathways following UV excitation of selected heterocycles, DNA bases, nucleosides and base-pairs in the gas phase.
Ashfold, Michael N R   +3 more
core   +2 more sources

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