Synergistic Cellular Toxicity from Inhibition of Poly(ADP-ribose) Glycohydrolase (PARG) and Ubiquitin-Specific Protease 1 (USP1). [PDF]
ToxicsLeonard SM +3 more
europepmc +1 more source
Calcium and Nitrogen Availability Controls Root Exudation in Hydroponically Cultured Barley
Plant, Cell &Environment, EarlyView.ABSTRACT Root exudation is a key component of plant‐rhizosphere interactome. It is increasingly evident that root exudates influence rhizospheric microbial communities and in turn can benefit plants through improved resource allocation. However, how suboptimal nutrient availability relates to control of root exudation is poorly understood.
Ibadete Denjali +6 more
wiley +1 more source
Effects of spironolactone on cytotoxic damage in osteoblasts. [PDF]
Exp Ther MedPark SY +5 more
europepmc +1 more source
Arabidopsis DXO1‐ and RNMT1‐Mediated m7G Capping of mRNA Modulates ABA Response
Plant, Cell &Environment, EarlyView.ABSTRACT Eukaryotic mRNA carries an N7‐methylguanosine (m⁷G) 5′ cap that is essential for mRNA stability and function. Although traditionally viewed as a constitutive process, m⁷G capping is increasingly recognized as dynamically regulated to control gene expression in response to environmental stimuli.
Shumin Liang +10 more
wiley +1 more source
Metabolic isotopic labeling of (deoxy)ribose enables dual neutral loss scanning for profiling nucleic acid modifications. [PDF]
Nucleic Acids ResRong SQ +7 more
europepmc +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photochemistry and Photobiology, EarlyView.Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source
Vascular Protection of Poly(ADP-ribose) Polymerase Inhibitors in the Combination Therapy With Vascular Endothelial Growth Factor Signaling Pathway Inhibitors. [PDF]
Rev Cardiovasc MedMa J +8 more
europepmc +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
Photochemistry and Photobiology, EarlyView.UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source
Plant Biology, EarlyView.Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley +1 more source
Protocol for synthesizing and purifying short-length poly(ADP)ribose polymer using fast protein liquid chromatography. [PDF]
STAR ProtocNeeharika S, Hanuman DS, Rajakumara E.
europepmc +1 more source