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Mutational Robustness of Ribosomal Protein Genes

Science, 2010
Keeping Fit Mutations may be deleterious, neutral, or advantageous. Understanding the relative effect of a new mutation on an organism's fitness is important for many systems from complex diseases to conservation biology. Lind et al.
Peter A, Lind   +2 more
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Ribosomal RNA gene transcription in trypanosomes

Parasitology Research, 2014
Leishmania major, Trypanosoma cruzi and Trypanosoma brucei are pathogenic species from the order Kinetoplastida. The molecular and cellular studies of parasites, such as of the biosynthesis of essential macromolecules, are important in designing successful strategies for control.
Roberto, Hernández   +1 more
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The Ribosomal Genes of Plasmodium

1986
Publisher Summary The chapter describes the Plasmodium rDNA unit. The chapter discusses briefly a feature of the rDNA units of other eukaryotic organisms and then compares and contrasts this with what has been found about the Plasmodium rDNA unit.
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Expression of Ribosomal Genes in Bacteria

1982
Publisher Summary This chapter discusses the molecular genetics of ribosomal proteins (r-proteins) and ribosomal ribonucleic acid (rRNA) in E. coli. Several molecular mechanisms for regulating r-protein and rRNA synthesis include autogenous regulation of r-protein operons by key regulatory r-proteins encoded by the operon, which they regulate ...
L, Lindahl, J M, Zengel
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Nuclear Ribosomal RNA Genes: ITS Region

2013
Despite possible drawbacks (intraspecific polymorphisms and possible fungal contamination), sequencing of the ribosomal RNA gene ITS region remains one of the most popular nuclear sequences used for plant taxonomy and phylogeny. A protocol for PCR amplification and sequencing of this region using universal plant primers is provided.
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On ribosomal gene compensation in Drosophila

Cell, 1980
Recent studies indicate that genes from only one nucleolus organizer undergo replication during polytenization of salivary gland cells of X/Y flies. This report presents evidence that this is also true X/X polytene cells. Interstrain hybrids were constructed which contain X chromosomes with different rDNA hybridization patterns following digestion with
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Transcription of Ribosomal Genes

1985
Transcription of rRNA genes is the first step in ribosome biogenesis and therefore is crucial in the understanding of the molecular and cellular aspects of ribosome production. Moreover, a specialized cell structure—the nucleolus—is built at the site of the active rRNA genes.
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Mammalian Ribosomal Gene Transcription

1989
Ribosomal RNA genes belong to the most actively transcribed genes of the cell. Actually, transcription of ribosomal DNA (rDNA) constitutes about 50% of cellular RNA syntheses. This extraordinarily high transcriptional activity reflects the need of the cell to produce more than a million ribosomes per cell cycle.
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The Ribosomal RNA Genes of Plasmodium

1994
Publisher Summary This chapter focuses on the ribosomal RNA (rRNA) genes of plasmodium. The study of rRNA genes offers the biologist at least three possible research areas: (1) molecular biology, (2) molecular inference of phylogeny based upon molecular sequence data, and (3) rRNA-based specific detection of organisms, which can be used ...
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Transcription of eukaryotic ribosomal RNA gene

Molecular and Cellular Biochemistry, 1986
Remarkable advances have been made in the identification of the promoter regions for the ribosomal RNA genes from lower and higher eukaryotes. There has been some progress in the elucidation of the factors that control transcription of the ribosomal RNA gene.
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