Results 31 to 40 of about 5,836,775 (343)

Role of the RNA-binding protein ZC3H41 in the regulation of ribosomal protein messenger RNAs in trypanosomes

open access: yesParasites & Vectors, 2023
Background Trypanosomes are single-celled eukaryotes that rely heavily on post-transcriptional mechanisms to regulate gene expression. RNA-binding proteins play essential roles in regulating the fate, abundance and translation of messenger RNAs (mRNAs ...
Gloria Ceballos-Pérez   +3 more
doaj   +1 more source

Probing the antioxidant activity of functional proteins and bioactive peptides in Hermetia illucens larvae fed with food wastes

open access: yesScientific Reports, 2022
Food waste is becoming more prevalent, and managing it is one of the most important issues in terms of food safety. In this study, functional proteins and bioactive peptides produced from the enzymatic digestion of black soldier fly (Hermetia illucens L.,
Jiaxin Lu   +6 more
doaj   +1 more source

Principles of cellular resource allocation revealed by condition-dependent proteome profiling

open access: yeseLife, 2017
Growing cells coordinate protein translation with metabolic rates. Central to this coordination is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribosomal proteins.
Eyal Metzl-Raz   +5 more
doaj   +1 more source

Ribosomal Protein uS5 and Friends: Protein–Protein Interactions Involved in Ribosome Assembly and Beyond

open access: yesBiomolecules, 2023
Ribosomal proteins are fundamental components of the ribosomes in all living cells. The ribosomal protein uS5 (Rps2) is a stable component of the small ribosomal subunit within all three domains of life.
Anne-Marie Landry-Voyer   +3 more
doaj   +1 more source

Tau drives translational selectivity by interacting with ribosomal proteins

open access: yesActa Neuropathologica, 2019
There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo.
Shon A. Koren   +10 more
semanticscholar   +1 more source

Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

open access: yesEMBO Journal, 2019
Tau is a scaffolding protein that serves multiple cellular functions that are perturbed in neurodegenerative diseases, including Alzheimer's disease (AD) and frontotemporal dementia (FTD). We have recently shown that amyloid‐β, the second hallmark of AD,
H. Evans   +4 more
semanticscholar   +1 more source

A preliminary Histochimecal study on proteins, lipids, and oxygen-deficient ribosomal DNA in Khawia grypi [PDF]

open access: yesمجلة التربية والعلم, 2005
In this research, a histochemical study was undertaken on a caryophyllidian , Khawia grypi, recently described from Barbus grypus .The materials detected were: protein using mercuric bromophenol blue, lipids using Sudan black B , deoxyribonucleic acid ...
Sundus Al-Kallak, Zuhair Raheemo
doaj   +1 more source

On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

open access: yesbioRxiv, 2018
Ribosomes are known to be assembled in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding ribosomal proteins (RPs) in axons, far away from neuronal cell bodies.
Toshiaki Shigeoka   +15 more
semanticscholar   +1 more source

Ancestral Interactions of Ribosomal RNA and Ribosomal Proteins [PDF]

open access: yesBiophysical Journal, 2017
We have proposed that the ancient ribosome increased in size during early evolution by addition of small folding-competent RNAs. In this Accretion Model, small RNAs and peptides were subsumed onto subunit surfaces, gradually encasing and freezing previously acquired components.
Poorna Roy   +3 more
openaire   +3 more sources

Alterations in the ribosomal machinery in cancer and hematologic disorders

open access: yesJournal of Hematology & Oncology, 2012
Ribosomes are essential components of the protein translation machinery and are composed of more than 80 unique large and small ribosomal proteins. Recent studies show that in addition to their roles in protein translation, ribosomal proteins are also ...
Shenoy Niraj   +6 more
doaj   +1 more source

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