Biomolecules, 2023 Ribosomal proteins are fundamental components of the ribosomes in all living cells. The ribosomal protein uS5 (Rps2) is a stable component of the small ribosomal subunit within all three domains of life.
Anne-Marie Landry-Voyer +3 more
doaj +1 more source
Tau drives translational selectivity by interacting with ribosomal proteins
Acta Neuropathologica, 2019 There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo.
Shon A. Koren +10 more
semanticscholar +1 more source
The other lives of ribosomal proteins
Human Genomics, 2010 Despite the fact that ribosomal proteins are the constituents of an organelle that is present in every cell, they show a surprising level of regulation, and several of them have also been shown to have other extra-ribosomal functions, such in replication,
Bhavsar Rital B +2 more
doaj +1 more source
A preliminary Histochimecal study on proteins, lipids, and oxygen-deficient ribosomal DNA in Khawia grypi [PDF]
مجلة التربية والعلم, 2005 In this research, a histochemical study was undertaken on a caryophyllidian , Khawia grypi, recently described from Barbus grypus .The materials detected were: protein using mercuric bromophenol blue, lipids using Sudan black B , deoxyribonucleic acid ...
Sundus Al-Kallak, Zuhair Raheemo
doaj +1 more source
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
bioRxiv, 2018 Ribosomes are known to be assembled in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding ribosomal proteins (RPs) in axons, far away from neuronal cell bodies.
Toshiaki Shigeoka +15 more
semanticscholar +1 more source
Protein escape at the ribosomal exit tunnel: Effect of the tunnel shape [PDF]
J. Chem. Phys. 153, 045105 (2020), 2020 We study the post-translational escape of nascent proteins at the ribosomal exit tunnel with the consideration of a real shape atomistic tunnel based on the Protein Data Bank (PDB) structure of the large ribosome subunit of archeon Haloarcula marismortui.
arxiv +1 more source
Revising the Structural Diversity of Ribosomal Proteins Across the Three Domains of Life
Molecular biology and evolution, 2018 Ribosomal proteins are indispensable components of a living cell, and yet their structures are remarkably diverse in different species. Here we use manually curated structural alignments to provide a comprehensive catalog of structural variations in ...
S. Melnikov +2 more
semanticscholar +1 more source
Alterations in the ribosomal machinery in cancer and hematologic disorders
Journal of Hematology & Oncology, 2012 Ribosomes are essential components of the protein translation machinery and are composed of more than 80 unique large and small ribosomal proteins. Recent studies show that in addition to their roles in protein translation, ribosomal proteins are also ...
Shenoy Niraj +6 more
doaj +1 more source
Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5. [PDF]
PLoS ONE, 2020 Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues.
Nusrat Rahman +2 more
doaj +1 more source
Ribosomal Proteins Control or Bypass p53 during Nucleolar Stress
International Journal of Molecular Sciences, 2017 The nucleolus is the site of ribosome biogenesis, a complex process that requires the coordinate activity of all three RNA polymerases and hundreds of non-ribosomal factors that participate in the maturation of ribosomal RNA (rRNA) and assembly of small ...
A. Russo, G. Russo
semanticscholar +1 more source