Results 141 to 150 of about 25,784 (242)
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley +1 more source
Editorial: Toxic Plant Proteins as Experimental Drugs for Human Pathologies
Letizia Polito +3 more
doaj +1 more source
Alteraciones histológicas causadas por la administración intraperitoneal de ebulina en ratones [PDF]
La ebulina es una proteína inhibidora de ribosomas tipo 2 con actividad lectina (RIL) aislada del saúco enano. Los frutos del saúco se han consumido desde la antigüedad por sus atribuidos efectos medicinales.
Vicente Pardo, Andrea
core
Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza +13 more
wiley +1 more source
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari +5 more
wiley +1 more source
A case of accidental Ricin poisoning [PDF]
A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Cachia, Mario J., Despott, Edward
core
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
Isolation and Characterization of Lectins from Ricinus communis [PDF]
Lectins are proteins which are well distributed in nature. They are found in both plants and animals but plants are the richest source. On the surface of the cell lectins are attached with their sugar binding site. Lectins are found to be toxic, as it is
Bhoi, Archana
core
State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding +6 more
wiley +1 more source
Biomimetic nanoparticles (BNPs) combine liposomal biocompatibility with cell‐mimicking functions for targeted delivery. This study compares turbulent jet mixing, microfluidic mixing, and extrusion for BNP fabrication. Characterization, proteomics, and in vitro assays show that turbulent jet and microfluidic mixing produce stable, protein‐enriched ...
Ilana Elizarov +3 more
wiley +1 more source

