Results 21 to 30 of about 358,575 (311)
Molecular Simulations of the Ribosome and Associated Translation Factors [PDF]
arXiv, 2017 The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information.
Hamed H. Alsulami (532535) +3 more
core +4 more sources
Ribosome biogenesis factors—from names to functions
EMBO Journal, 2023 The assembly of ribosomal subunits is a highly orchestrated process that involves a huge cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified by genetic screens and proteomic approaches of pre‐ribosomal particles
K. Dörner +3 more
semanticscholar +1 more source
Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance
Cancer Research, 2022 Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA translation machines. Ribosome biogenesis is a multistep process that begins in the nucleolus and concludes in the cytoplasm.
Amr R Elhamamsy +4 more
semanticscholar +1 more source
The channel capacity of the ribosome [PDF]
Phys. Rev. E 108, 044404 (2023), 2023 Translation is one of the most fundamental processes in the biological cell. Because of the central role that translation plays across all domains of life, the enzyme that carries out this process, the ribosome, is required to process information with high accuracy. This accuracy often approaches values near unity experimentally.
arxiv +1 more source
Impact of Ribosome Activity on SARS-CoV-2 LNP – Based mRNA Vaccines
Frontiers in Molecular Biosciences, 2021 Coronavirus-related Severe Acute Respiratory Syndrome-2 (SARS-CoV-2) initially was detected in Wuhan, Hubei, China. Since early 2021, World Health Organization (WHO) has declared Coronavirus Disease 2019 (COVID-19) a pandemic due to rapidly transformed ...
Evangelos Tsiambas +11 more
doaj +1 more source
Mass spectrometry of ribosomes and ribosomal subunits [PDF]
Proceedings of the National Academy of Sciences, 1998 Nanoflow electrospray ionization has been used to introduce intact Escherichia coli ribosomes into the ion source of a mass spectrometer. Mass spectra of remarkable quality result from a partial, but selective, dissociation of the particles within the mass spectrometer.
Benjamin, DR +4 more
openaire +4 more sources
Extraribosomal Functions of Cytosolic Ribosomal Proteins in Plants
Frontiers in Plant Science, 2021 Ribosomes are basic translational machines in all living cells. The plant cytosolic ribosome is composed of four rRNAs and approximately 81 ribosomal proteins (RPs). In addition to the fundamental functions of RPs in the messenger RNA decoding process as
Wei Xiong +4 more
doaj +1 more source
Separation and Paired Proteome Profiling of Plant Chloroplast and Cytoplasmic Ribosomes
Plants, 2020 Conventional preparation methods of plant ribosomes fail to resolve non-translating chloroplast or cytoplasmic ribosome subunits from translating fractions.
Alexandre Augusto Pereira Firmino +7 more
doaj +1 more source
Mediating Ribosomal Competition by Splitting Pools [PDF]
LCSS Vol 5 Issue 5 (Nov 2020), 2020 Synthetic biology constructs often rely upon the introduction of "circuit" genes into host cells, in order to express novel proteins and thus endow the host with a desired behavior. The expression of these new genes "consumes" existing resources in the cell, such as ATP, RNA polymerase, amino acids, and ribosomes. Ribosomal competition among strands of
arxiv +1 more source
The ABCs of the ribosome [PDF]
Nature Structural & Molecular Biology, 2014 An ABC protein that binds the ribosomal exit site suggests a new mechanism for direct regulation of translation in response to changing ATP levels in the cell.
Fredrick, Kurt, Ibba, Michael
openaire +4 more sources