Results 61 to 70 of about 254,623 (219)

Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors

open access: yeseLife, 2021
Human mitochondria express a genome that encodes thirteen core subunits of the oxidative phosphorylation system (OXPHOS). These proteins insert into the inner membrane co-translationally. Therefore, mitochondrial ribosomes engage with the OXA1L-insertase
Sven Dennerlein   +12 more
doaj   +1 more source

A Network-Guided Genetic Approach to Identify Novel Regulators of Adventitious Root Formation in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2019
Adventitious roots (ARs) are formed de novo during post-embryonic development from non-root tissues, in processes that are highly dependent on environmental inputs.
Sergio Ibáñez   +8 more
doaj   +1 more source

On the Ribosomal Density that Maximizes Protein Translation Rate [PDF]

open access: yes, 2016
During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein production rate. A natural and important question is what ribosomal density maximizes the protein production rate.
arxiv   +1 more source

The ribosome returned [PDF]

open access: yesJournal of Biology, 2009
Since the mid-1990s, insights obtained from electron microscopy and X-ray crystallography have transformed our understanding of how the most important ribozyme in the cell, the ribosome, catalyzes protein synthesis. This review provides a brief account of how this structural revolution came to pass, and the impact it has had on our understanding of how
openaire   +3 more sources

Aging in Rats Differentially Affects Markers of Transcriptional and Translational Capacity in Soleus and Plantaris Muscle

open access: yesFrontiers in Physiology, 2017
Alterations in transcriptional and translational mechanisms occur during skeletal muscle aging and such changes may contribute to age-related atrophy. Herein, we examined markers related to global transcriptional output (i.e., myonuclear number, total ...
Christopher B. Mobley   +18 more
doaj   +1 more source

Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition

open access: yeseLife, 2021
During embryogenesis, Hox mRNA translation is tightly regulated by a sophisticated molecular mechanism that combines two RNA regulons located in their 5’UTR. First, an internal ribosome entry site (IRES) enables cap-independent translation.
Fatima Alghoul   +3 more
doaj   +1 more source

The 73 S ribosome of Neurospora crassa is the native mitochondrial ribosome [PDF]

open access: yes, 1977
The effect of the inclusion of EDTA and of heparin, in media used in the isolation of mitochondria, on the mitochindrial previous termribosomenext term has been investigated. 1. 1.
Adelmann   +24 more
core   +1 more source

Exploring Wells-Dawson Clusters Associated With the Small Ribosomal Subunit

open access: yesFrontiers in Chemistry, 2019
The polyoxometalate P2W18O626-, the Wells-Dawson cluster, stabilized the ribosome sufficiently for the crystallographers to solve the phase problem and improve the structural resolution.
Debbie C. Crans   +3 more
doaj   +1 more source

Functional Analysis of PSRP1, the Chloroplast Homolog of a Cyanobacterial Ribosome Hibernation Factor

open access: yesPlants, 2020
Bacterial ribosome hibernation factors sequester ribosomes in an inactive state during the stationary phase and in response to stress. The cyanobacterial ribosome hibernation factor LrtA has been suggested to inactivate ribosomes in the dark and to be ...
Kevin Swift   +4 more
doaj   +1 more source

Genome-wide Survey of Ribosome Collision

open access: yesCell Reports, 2020
Summary: Ribosome movement is not always smooth and is rather often impeded. For ribosome pauses, fundamental issues remain to be addressed, including where ribosomes pause on mRNAs, what kind of RNA/amino acid sequence causes this pause, and the ...
Peixun Han   +10 more
doaj  

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