Results 201 to 210 of about 88,539 (283)

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source

Supplementary Figure 10 from Oncogenic Cells of Renal Embryonic Lineage Sensitive to the Small-Molecule Inhibitor QC6352 Display Depletion of KDM4 Levels and Disruption of Ribosome Biogenesis

Prahalathan Pichavaram, Carolyn M. Jablonowski, Jie Fang, Andrew M. Fleming, Hyea Jin Gil, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Christopher L. Morton, Gerard P. Zambetti, Andrew M. Davidoff, Jun Yang, Andrew J. Murphy   +13 more
openalex   +1 more source

Integrating Transcriptomics and Gut Microbiota Analysis Reveals the Anti‐Osteoporotic Mechanisms of Wine and Oil Co‐Processed Epimedium

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Firstly, we determined the content of the components in the co‐products of Epimedium wine and oil. Secondly, the clinical indications of the co‐products of Epimedium wine and oil were determined by in vitro cell experiments. Finally, the in vivo animal model was used for experimental verification.
Jinling Liang, Shichang Li, Yulin Dai, Zifeng Pi, Jia Liu, Pan Li, Weixia Sun, Tao Jiang, Tianyang Xu, Peng Yu   +9 more
wiley   +1 more source

Ribosome biogenesis in plants requires the nuclear envelope and mitochondria localized OPENER complex. [PDF]

Nat Commun
Wang W, Mahboubi A, Zhu S, Hanson J, Mateus A, Niittylä T.   +5 more
europepmc   +1 more source

Supplementary Data S2 from BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma

Keiji Kurata, Mehmet Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gullà, Yu‐Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson   +11 more
openalex   +1 more source

Regulation of SirT1-Nucleomethylin Binding by rRNA Coordinates Ribosome Biogenesis with Nutrient Availability [PDF]

, 2013
Leixiang Yang, Tanjing Song, Lihong Chen, Neha Kabra, Hong Zheng, John M. Koomen, Edward Seto, Jiandong Chen   +7 more
openalex   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay, Sajin Marcus Cyr, Yorihiro Iwasaki, Elizabeth Hill, Eugene P. Rhee, Nevil J. Singh, Petra Simic, Murat Bastepe   +7 more
wiley   +1 more source

PCDHGB7 inhibits the progression of triple-negative breast cancer by suppressing XRCC5/MYC-mediated ribosome biogenesis. [PDF]

Clin Transl Med
Shan M, Bi H, Sun H, Li Y, Li Z, Wang Z, Dong J, Sang S, Ren L, Ye Y, Wang T, Volarević S, Su R, Zhang L, Zhang M, He Y, Zhang G, Li J, Li X.   +18 more
europepmc   +1 more source

Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function [PDF]

Shuxu Wei, Ronghuai Shen, Xiaojia Lu, Xinyi Li, Lingbin He, Yu Zhang, Jiahang Yang, Zhouwu Shu, Xianxi Huang   +8 more
openalex   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source