Results 231 to 240 of about 88,539 (283)

Eukaryotic ribosome biogenesis at a glance

, 2013
Emma Thomson, Sébastien Ferreira-Cerca, Ed Hurt   +2 more
openalex   +2 more sources

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

Combined targeting poly (ADP-ribose) polymerase and receptor tyrosine kinase inhibits ovarian clear cell carcinoma progression through disrupted ribosome biogenesis. [PDF]

J Mol Med (Berl)
Lin CY, Chao AS, Chao A, Wu RC, Yu AL, Fu CH, Teng YC, Huang RY, Lai CH.   +8 more
europepmc   +1 more source

Effect of aberrant ribosome biogenesis on wild-type and mutant p53 in cancer cells

, 2014
Marco Dal Ferro
openalex   +1 more source

Using Mathematical Modeling of Tumor Metabolism to Predict the Magnitude, Composition, and Hypoxic Interactions of Microenvironment Acidosis

BioEssays, Volume 48, Issue 1, January 2026.
Mathematical model of a perfused cylindrical tumor predicts venous‐end extracellular [O2], pH, [CO2], and [HCO3−] in the case of either fermentative or respiratory metabolism, illustrating the relationship between hypoxia and acidosis and the chemical composition of acidosis in the tumor microenvironment. ABSTRACT In well‐perfused tissues, interstitial
Alzbeta Hulikova, Pawel Swietach
wiley   +1 more source

Ribosome Biogenesis Underpins Tumor Progression: A Comprehensive Signature for Survival and Immunotherapy Response Prediction. [PDF]

Cancers (Basel)
Elhamamsy AR, Aly SM, Samant RS, Shevde LA.   +3 more
europepmc   +1 more source

Mechanistic Insights and Therapeutic Potential of Small Nucleolar RNA Host Genes in the Carcinogenesis of Hepatocellular Carcinoma

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is one of the major factors endangering human health due to its poor prognosis, resulting from difficulties in early diagnosis and lack of effective treatment measures. Long non‐coding RNAs (lncRNAs), which are RNA molecules that do not translate into proteins, play essential roles in various tumor ...
Jiajia Luo, Zhangxiu Liao, Shuangxia Zhang   +2 more
wiley   +1 more source

Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction. [PDF]

Front Immunol
Chen J, Zhang D, Zhu C, Lin L, Ye K, Hua Y, Peng M.   +6 more
europepmc   +1 more source

Fluorescent Dyes for Probing Intracellular and Subcellular Polarity

Chemistry–Methods, Volume 6, Issue 1, January 2026.
Fluorescent probes are crucial tools for measuring cellular microenvironment polarity, a parameter that influences physiological organelle function and diseases such as cancer. This text details the probes' physicochemical principles, intracellular targeting strategies, and key photophysical parameters for polarity estimation.
M. Carmen Gonzalez‐Garcia, Maria J. Ruedas‐Rama, Juan A. González‐Vera, Emilio Garcia‐Fernandez, Angel Orte   +4 more
wiley   +1 more source