Results 241 to 250 of about 173,360 (283)

Sequestration of ribosome biogenesis factors in HSV-1 nuclear aggregates revealed by spatially resolved thermal profiling. [PDF]

Sci Adv
Metzger PJ, Reed TJ, Lum KK, Botello JF, Jiang L, Brangwynne CP, Troyanskaya OG, Cristea IM.   +7 more
europepmc   +1 more source

MtDNA‐depleted neuronal cell transcriptomes reveal Alzheimer's disease‐related changes

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION We determined whether mitochondrial DNA (mtDNA) depletion induced Alzheimer's disease (AD)‐relevant transcription changes. METHODS Following RNA sequencing (RNA‐seq), we identified differentially expressed genes (DEGs) between SH‐SY5Y or NT2 mtDNA‐depleted (ρ0) and intact (ρ+) cell lines and quantified concordant DEG changes. Gene
Blaise W. Menta, Emily Schueddig, Amol Ranjan, Yanming Li, Shea J. Andrews, Heather M. Wilkins, Dong Pei, Russell H. Swerdlow   +7 more
wiley   +1 more source

RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma. [PDF]

J Transl Med
Pan H, Liao L, Xu S, Xu Y, Chai W, Liu X, Li J, Cao Y, Sun L, Liu Q, Yan M.   +10 more
europepmc   +1 more source

Noncoding RNAs in Host–Microbiota Interaction

Animal Research and One Health, Volume 3, Issue 4, Page 358-367, November 2025.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao, Ni Li, Jingyi Xu, Jianrong Ren, Xiaojun Yang, Xinyi Li, Junhu Yao, Shengru Wu   +7 more
wiley   +1 more source

Targeting Ribosome Biogenesis for Cancer Therapy with Oral Platinum Complexes. [PDF]

JACS Au
Song D, Wang X, Zhao Z, Yang R, Zhang S, Guo Z.   +5 more
europepmc   +1 more source

Exploring Contraindicated Medications and Corresponding Targeted Genes for Migraine Through Integrated Genetic Approaches

Brain and Behavior, Volume 15, Issue 11, November 2025.
To systematically identify risk medications for migraine and its subtypes, we integrated GWAS data for 23 medications with GWASs of migraine and its subtypes to conduct causal inference. We then combined plasma eQTLs with drug‐target databases to map putative targets of the risk medications and validated causal relationships using colocalization and ...
Nan Wang, Weixuan Liang, Zhuofeng Wen, Wanzhe Liao, Zhixin Xie, Zhiyi Zhou, Ziyang Yang, Xitong Ju, Haobin Zhou, Chuiguo Huang   +9 more
wiley   +1 more source

Acetylation of microtubule-binding PinX1 orchestrates ribosome biogenesis to nutrient starvation via the RNA polymerase I preinitiation complex. [PDF]

J Biol Chem
Lu G, Yang L, Zhang Q, Zhang S, Xiong Y, Li T, Zhang Y, Liu M, Zhang Y, Wu J, Weng Q, Liu X, Ji J, Wang H, Luo J.   +14 more
europepmc   +1 more source

Eukaryotic ribosome biogenesis at a glance

, 2013
Emma Thomson, Sébastien Ferreira-Cerca, Ed Hurt   +2 more
openalex   +2 more sources

m7G RNA methylation in cancer: Effect, mechanism and clinical application

Clinical and Translational Medicine, Volume 15, Issue 11, November 2025.
m7G RNA methylation in cancer. m7G regulates various tumour‐related biological processes, including cell proliferation, metabolism, drug sensitivity, invasion, migration, immune evasion and anti‐tumour. Abstract Background RNA methylation has emerged as a pivotal layer of post‐transcriptional regulation that shapes the biological behavior of cancer ...
PengYuan Dang, KaiBo Li, ZhenQiang Sun
wiley   +1 more source