Results 241 to 250 of about 88,539 (283)

Transcriptomic Responses of the Marine Diatom Phaeodactylum tricornutum to High Carbon and Low Nitrogen Stress

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
To elucidate the integrated transcriptional mechanisms underlying diatom acclimation to coupled carbon–nitrogen (CN) imbalance, we employed RNA sequencing (RNA‐Seq) to characterize the global transcriptional response of the model diatom Phaeodactylum tricornutum to high CO2 (~2000 μatm) and low nitrogen (10% of nitrogen concentration in f/2 medium ...
Yi Zhang   +6 more
wiley   +1 more source

Pattern of Detections Across Multiple Environmental Messenger RNAs (e‐mRNAs) in Stressor‐Exposed Zebrafish (Danio rerio)

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
We evaluated e‐mRNAs of known molecular targets of perfluorooctanesulfonic acid (PFOS) toxicity in zebrafish in a controlled laboratory experiment. The detection patterns of e‐mRNAs in our study imply that diminishing detection of these traces over time is a strong indicator of target organism presence (or very recent presence), providing a narrower ...
Denise L. Lindsay   +4 more
wiley   +1 more source

Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal   +10 more
wiley   +1 more source

High‐Dose Parenteral Iron Corrects Iron Deficiency Anemia While Disrupting Gut Microbiota and Metabolic Homeostasis in Neonatal Piglets

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Our results indicate that although high‐dose parenteral iron effectively corrects iron deficiency anemia (IDA), it causes liver dysfunction, immune suppression, systemic iron overload, and altered gut microbiota. ABSTRACT Iron deficiency anemia (IDA) is a common nutritional disorder in mammals, particularly affecting neonates and neonatal piglets ...
Qian Zhang   +4 more
wiley   +1 more source

The RNA-binding protein PRRC2B preserves 5' TOP mRNA during starvation to maintain ribosome biogenesis during nutrient recovery. [PDF]

open access: yesNucleic Acids Res
Goldberg N   +7 more
europepmc   +1 more source

hiPSC‐Derived Astrocytes From Individuals With Schizophrenia Induce a Dystrophic Phenotype in Microglial‐Like Cells

open access: yesGlia, Volume 74, Issue 1, January 2026.
SCZ astrocytes display an increased pro‐inflammatory profile upon TNF‐α stimulation. Reactive SCZ astrocytes induce microglial‐like cells to assume a dystrophic phenotype. Reactive SCZ astrocytes limit iMGs' synaptoneurosome uptake and migration. ABSTRACT Neuroinflammation, particularly astrocyte reactivity, is increasingly linked to schizophrenia (SCZ)
Pablo L. Cardozo   +18 more
wiley   +1 more source

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