Results 31 to 40 of about 173,360 (283)

A truncated variant of the ribosome-associated trigger factor specifically contributes to plant chloroplast ribosome biogenesis. [PDF]

Nat Commun
Ries F, Gorlt J, Kaiser S, Scherer V, Seydel C, Nguyen S, Klingl A, Legen J, Schmitz-Linneweber C, Plaggenborg H, Ng JZY, Wiens D, Hochberg GKA, Räschle M, Möhlmann T, Scheuring D, Willmund F.   +16 more
europepmc   +3 more sources

A Comparative Perspective on Ribosome Biogenesis: Unity and Diversity Across the Tree of Life.

Methods in molecular biology, 2022
Ribosomes are universally conserved ribonucleoprotein complexes involved in the decoding of the genetic information contained in messenger RNAs into proteins.
Michael Jüttner, Sébastien Ferreira-Cerca   +1 more
semanticscholar   +1 more source

Peptides Targeting the Interaction Between Erb1 and Ytm1 Ribosome Assembly Factors

Frontiers in Molecular Biosciences, 2021
Ribosome biogenesis is an emerging therapeutic target. It has been proposed that cancer cells are addicted to ribosome production which is therefore considered a druggable pathway in cancer therapy.
Lidia Orea-Ordóñez, Susana Masiá, Jerónimo Bravo   +2 more
doaj   +1 more source

Expression Profiling of Ribosome Biogenesis Factors Reveals Nucleolin as a Novel Potential Marker to Predict Outcome in AML Patients. [PDF]

PLoS ONE, 2017
Acute myeloid leukemia (AML) is a heterogeneous disease. Prognosis is mainly influenced by patient age at diagnosis and cytogenetic alterations, two of the main factors currently used in AML patient risk stratification.
Virginie Marcel, Frédéric Catez, Caroline M Berger, Emeline Perrial, Adriana Plesa, Xavier Thomas, Eve Mattei, Sandrine Hayette, Pierre Saintigny, Philippe Bouvet, Jean-Jacques Diaz, Charles Dumontet   +11 more
doaj   +1 more source

Translational GTPase BipA Is Involved in the Maturation of a Large Subunit of Bacterial Ribosome at Suboptimal Temperature

Frontiers in Microbiology, 2021
BPI-inducible protein A (BipA), a highly conserved paralog of the well-known translational GTPases LepA and EF-G, has been implicated in bacterial motility, cold shock, stress response, biofilm formation, and virulence.
Kwok Jian Goh, Rya Ero, Xin-Fu Yan, Jung-Eun Park, Binu Kundukad, Jun Zheng, Siu Kwan Sze, Yong-Gui Gao   +7 more
doaj   +1 more source

VIRMA-mediated m⁶A modification regulates forebrain formation through modulating ribosome biogenesis. [PDF]

Sci Adv
Wu M, Wu X, Sun H, Wang W, Zhang L, Liu X, Zhang Y, Zhang X, Liu J, Shen B, Zhou T.   +10 more
europepmc   +2 more sources

SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer

Nature Communications, 2021
SOD1 is known as the major cytoplasmic superoxide dismutase and an anticancer target. However, the role of SOD1 in cancer is not fully understood. Herein we describe the generation of an inducible Sod1 knockout in KRAS-driven NSCLC mouse model.
Xiaowen Wang, Hong Zhang, Russell T Sapio, Jun Yang, Justin S. B. Wong, Xin Zhang, J. Y. Guo, Sharon R. Pine, H. Van Remmen, H. Li, E. White, Chen Liu, M. Kiledjian, D. Pestov, X. F. Steven Zheng   +14 more
semanticscholar   +1 more source

Does the blunted stimulation of skeletal muscle protein synthesis by aging in response to mechanical load result from impaired ribosome biogenesis?

Frontiers in Aging, 2023
Age-related loss of skeletal muscle mass leads to a reduction of strength. It is likely due to an inadequate stimulation of muscle protein synthesis (MPS) in response to anabolic stimuli, such as mechanical load.
Thomas Chaillou, Diego Montiel-Rojas
doaj   +1 more source

Eukaryotic Ribosome Biogenesis: The 40S Subunit

Acta Naturae, 2022
The formation of eukaryotic ribosomes is a sequential process of ribosomal precursors maturation in the nucleolus, nucleoplasm, and cytoplasm. Hundreds of ribosomal biogenesis factors ensure the accurate processing and formation of the ribosomal RNAs ...
Anastasia A. Moraleva, Alexander Deryabin, Y. Rubtsov, M. Rubtsova, O. Dontsova   +4 more
semanticscholar   +1 more source

Separation and Paired Proteome Profiling of Plant Chloroplast and Cytoplasmic Ribosomes

Plants, 2020
Conventional preparation methods of plant ribosomes fail to resolve non-translating chloroplast or cytoplasmic ribosome subunits from translating fractions.
Alexandre Augusto Pereira Firmino, Michal Gorka, Alexander Graf, Aleksandra Skirycz, Federico Martinez-Seidel, Kerstin Zander, Joachim Kopka, Olga Beine-Golovchuk   +7 more
doaj   +1 more source