Results 11 to 20 of about 142,894 (282)
Ribosome Biogenesis Alterations in Colorectal Cancer [PDF]
Cells, 2020 Many studies have focused on understanding the regulation and functions of aberrant protein synthesis in colorectal cancer (CRC), leaving the ribosome, its main effector, relatively underappreciated in CRC.
Sophie Nait Slimane +7 more
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RNase III, Ribosome Biogenesis and Beyond [PDF]
Microorganisms, 2021 The ribosome is the universal catalyst for protein synthesis. Despite extensive studies, the diversity of structures and functions of this ribonucleoprotein is yet to be fully understood.
Maxence Lejars +2 more
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, 2022 This Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic.
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Eukaryotic ribosome biogenesis at a glance [PDF]
Journal of Cell Science, 2013 International audienceRibosomes play a pivotal role in the molecular life of every cell. Moreover, synthesis of ribosomes is one of the most energetically demanding of all cellular processes.
Ferreira-Cerca, Sébastien +2 more
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Inhibiting eukaryotic ribosome biogenesis [PDF]
BMC Biology, 2019 Background Ribosome biogenesis is a central process in every growing cell. In eukaryotes, it requires more than 250 non-ribosomal assembly factors, most of which are essential.
Dominik Awad +9 more
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Ribosome biogenesis in disease: new players and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome biogenesis is the process that generates ribosomes and plays an essential role in cell proliferation, differentiation, apoptosis, development, and transformation. The mTORC1,
Lijuan Jiao +7 more
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Regulation of ribosome biogenesis within the nucleolus [PDF]
FEBS Letters, 2001 Ribosome biogenesis is both necessary for cellular adaptation, growth, and proliferation as well as a major energetic and biosynthetic demand upon cells. For these reasons, ribosome biogenesis requires precise regulation to balance supply and demand. The
Sui Huang +3 more
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Growth control and ribosome biogenesis.
Current Opinion in Cell Biology, 2009 Ribosomes provide the basis for protein production and this drives cell growth. Recent studies, both in yeast and in higher eukaryotes, are beginning to reveal new mechanisms underlying the elaborate control of ribosome biogenesis, which requires ...
Lempiäinen H, Shore D
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Research Progress of Ribosome Biogenesis and Cancer
Zhongliu Fangzhi Yanjiu, 2020 As an important biological process, ribosome biogenesis determines the rate of protein synthesis in cells. However, ribosome biogenesis is abnormally regulated in tumors under strong growth pressure.
QIAN Lili, ZHANG Honghe
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Cell Reports, 2023 Summary: Increased nucleolar size and activity correlate with aberrant ribosome biogenesis and enhanced translation in cancer cells. One of the first and rate-limiting steps in translation is the interaction of the 40S small ribosome subunit with mRNAs ...
M. Carmen Lafita-Navarro +20 more
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