Results 21 to 30 of about 57,712 (282)
Biomedicines, 2022 Ribosome biogenesis is a cellular process critical for protein homeostasis during cell growth and multiplication. Our previous study confirmed up-regulation of ribosome biogenesis during endometriosis progression and malignant transition, thus anti ...
Cherry Yin-Yi Chang +13 more
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Research Progress of Ribosome Biogenesis and Cancer
Zhongliu Fangzhi Yanjiu, 2020 As an important biological process, ribosome biogenesis determines the rate of protein synthesis in cells. However, ribosome biogenesis is abnormally regulated in tumors under strong growth pressure.
QIAN Lili, ZHANG Honghe
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snoRNPs: Functions in Ribosome Biogenesis [PDF]
Biomolecules, 2020 Ribosomes are perhaps the most critical macromolecular machine as they are tasked with carrying out protein synthesis in cells. They are incredibly complex structures composed of protein components and heavily chemically modified RNAs. The task of assembling mature ribosomes from their component parts consumes a massive amount of energy and requires ...
Sandeep Ojha +2 more
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Cell Reports, 2023 Summary: Increased nucleolar size and activity correlate with aberrant ribosome biogenesis and enhanced translation in cancer cells. One of the first and rate-limiting steps in translation is the interaction of the 40S small ribosome subunit with mRNAs ...
M. Carmen Lafita-Navarro +20 more
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Frontiers in Microbiology, 2021 Ribosome assembly is an essential and carefully choreographed cellular process. In eukaryotes, several 100 proteins, distributed across the nucleolus, nucleus, and cytoplasm, co-ordinate the step-wise assembly of four ribosomal RNAs (rRNAs) and ...
Mehmet Birikmen +8 more
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Peptides Targeting the Interaction Between Erb1 and Ytm1 Ribosome Assembly Factors
Frontiers in Molecular Biosciences, 2021 Ribosome biogenesis is an emerging therapeutic target. It has been proposed that cancer cells are addicted to ribosome production which is therefore considered a druggable pathway in cancer therapy.
Lidia Orea-Ordóñez +2 more
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Frontiers in Microbiology, 2021 BPI-inducible protein A (BipA), a highly conserved paralog of the well-known translational GTPases LepA and EF-G, has been implicated in bacterial motility, cold shock, stress response, biofilm formation, and virulence.
Kwok Jian Goh +7 more
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Post-transcriptional regulation of ribosome biogenesis in yeast [PDF]
, 2017 Most microorganisms are exposed to the constantly and often rapidly changing environment. As such they evolved mechanisms to balance their metabolism and energy expenditure with the resources available to them.
Martin Koš, Isabelle C. Kos-Braun
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BMC Cancer, 2022 Background A current critical need remains in the identification of prognostic and predictive markers in early breast cancer. It appears that a distinctive trait of cancer cells is their addiction to hyperactivation of ribosome biogenesis. Thus, ribosome
Flora Nguyen Van Long +30 more
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The small-subunit processome is a ribosome assembly intermediate [PDF]
, 2004 The small-subunit (SSU) processome is a large ribonucleoprotein required for the biogenesis of the 18S rRNA and likely corresponds to the terminal knobs visualized by electron microscopy on the 5' end of nascent rRNAs.
Granneman, Sander; id_orcid +4 more
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