Results 81 to 90 of about 142,894 (282)
Signal transduction in ribosome biogenesis: A recipe to avoid disaster [PDF]
, 2019 Energetically speaking, ribosome biogenesis is by far the most costly process of the cell and, therefore, must be highly regulated in order to avoid unnecessary energy expenditure.
Piazzi M. +4 more
core +2 more sources
Structural studies of ribosome stalling and translocation complexes [PDF]
, 2010 In this study, cryo-electron microscopy (cryo-EM) and single particle reconstruction were used as a main technique to investigate the involvement of bacterial ribosomes in two crucial cellular processes: the regulation of gene expression and the ...
Seidelt, Birgit
core +1 more source
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced ScienceStrict regulation of epithelial cells is crucial for maintaining intestinal barrier integrity and preventing intestinal diseases. While transcriptional regulation is well recognized as vital in this process, translational regulation is equally important.
Hanyu Rao +11 more
doaj +1 more source
, 2015 Ribosome biogenesis involves a large inventory of proteinaceous and RNA cofactors. More than 250 ribosome biogenesis factors (RBFs) have been described in yeast.
Mario Keller +7 more
core +1 more source
, 2012 ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Hopfner, Karl-Peter
core +1 more source
Advanced Science, EarlyView.Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang +8 more
wiley +1 more source
Regulation of ribosome biogenesis: Where is TOR? [PDF]
Cell Metabolism, 2006 Li et al., (2006) have shown that TOR complex 1 in yeast binds directly to the rDNA promoter and thereby activates Pol I-dependent synthesis of 35S RNA. This is an important advance in the understanding of how ribosome biogenesis is regulated in response to environmental conditions.
Martin, D. E., Powers, T., Hall, M. N.
openaire +3 more sources
Downregulation of ribosome biogenesis during early forebrain development
eLife, 2018 Forebrain precursor cells are dynamic during early brain development, yet the underlying molecular changes remain elusive. We observed major differences in transcriptional signatures of precursor cells from mouse forebrain at embryonic days E8.5 vs.
Kevin F Chau +9 more
doaj +1 more source
Pipeline to quantify ribosome biogenesis activity
, 2023 Pipeline to quantify ribosome biogenesis activity based on transcriptome expression ...
Huajing Teng (17220052)
core +1 more source
Advanced Science, EarlyView.Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou +10 more
wiley +1 more source